CAS Number3065-79-0
Synonyms3,3′-Diethyl-9-methylthiacarbocyanine iodide; Benzothiazolium,3-ethyl-2-(3-(3-ethyl-2(3H)-benzothiazolylidene)-2-methyl-1-propenyl)-,iodide; 3-ethyl-2-[3-(3-ethyl-3H-benzothiazol-2-ylidene)-2-methyl-propenyl]-benzothiazolium,iodide; 1,3-Bis-(3-aethyl-benzothiazol-2-yl)-2-methyl-trimethinium,Jodid; MFCD00011955; 3,3'-Diethyl-9-methylthiocarbocyanin Iodid (11b); Benzothiazolium,3-ethyl-2-(3-(3-ethyl-2-benzothiazolinylidene)-2-methyl-1-propenyl)-,iodide; 1,3-bis-(3-ethyl-benzothiazol-2-yl)-2-methyl-trimethinium,iodide; 3,3'-Diethyl-9-methylthiacarbocyanine iodide; T0500-8750; 3-Ethyl-2-(3-(3-ethyl-3H-benzothiazol-2-ylidene)-2-methylprop-1-enyl)benzothiazolium iodide; 3-ethyl-2-[3-(3-ethyl-3H-2-benzothiazolylidene)-2-methyl-1-propenyl] benzothiazolium iodide; EINECS 221-317-2
Molecular FormulaC22H23IN2S2
Molecular Weight506.46600
Purity98.00%
Melting Point290ºC(dec.)(lit.)
Appearancebrown powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3065-79-0 |
| Catalog No. | 2A-9029376 |
| Chinese Name | 3,3'-二乙基-9-甲基硫杂羰花青碘化物 |
| Synonyms | 3,3′-Diethyl-9-methylthiacarbocyanine iodide; Benzothiazolium,3-ethyl-2-(3-(3-ethyl-2(3H)-benzothiazolylidene)-2-methyl-1-propenyl)-,iodide; 3-ethyl-2-[3-(3-ethyl-3H-benzothiazol-2-ylidene)-2-methyl-propenyl]-benzothiazolium,iodide; 1,3-Bis-(3-aethyl-benzothiazol-2-yl)-2-methyl-trimethinium,Jodid; MFCD00011955; 3,3'-Diethyl-9-methylthiocarbocyanin Iodid (11b); Benzothiazolium,3-ethyl-2-(3-(3-ethyl-2-benzothiazolinylidene)-2-methyl-1-propenyl)-,iodide; 1,3-bis-(3-ethyl-benzothiazol-2-yl)-2-methyl-trimethinium,iodide; 3,3'-Diethyl-9-methylthiacarbocyanine iodide; T0500-8750; 3-Ethyl-2-(3-(3-ethyl-3H-benzothiazol-2-ylidene)-2-methylprop-1-enyl)benzothiazolium iodide; 3-ethyl-2-[3-(3-ethyl-3H-2-benzothiazolylidene)-2-methyl-1-propenyl] benzothiazolium iodide; EINECS 221-317-2 |
| Molecular Formula | C22H23IN2S2 |
| Molecular Weight | 506.46600 |
| Purity | 98.00 |
| Melting Point | 290ºC(dec.)(lit.) |
| Appearance | brown powder |
| Storage Condition | Store airtight in a cool, dry warehouse. |
| Application | 3,3'-Diethyl-9-methylthiocarbocyanine iodide is a cyanine dye and a τ aggregation inhibitor, with an IC50 value of 0.28 μM. 3,3'-Diethyl-9-methylthiocarbocyanine iodide can cause dysfunction of the mi |
| PubChem ID | 553332 |
| SMILES | CCN1C(=CC(C)=Cc2sc3ccccc3[n+]2CC)Sc2ccccc21.[I-] |
| InChI | InChI=1S/C22H23N2S2.HI/c1-4-23-17-10-6-8-12-19(17)25-21(23)14-16(3)15-22-24(5-2)18-11-7-9-13-20(18)26-22;/h6-15H,4-5H2,1-3H3;1H/q+1;/p-1 |
| InChI Key | SAEMBGFHGROQJZ-UHFFFAOYSA-M |
| Bioactivity | 3,3'-Diethyl-9-methylthiacarbocyanine iodide is a cyanine dye, also a tau aggregation inhibitor, with an IC50 value of 0.28 μM for tau. 3,3'-Diethyl-9-methylthiacarbocyanine iodide can cause misfunction of the microtubule cytoskeleton. 3,3'-Diethyl-9-methylthiacarbocyanine iodide can be used for researching Alzheimer's disease[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin Research Areas >> Neurological Disease Target IC50: 0.28 μM (tau)[1] References [1]. Chang E, et al. Structure-activity relationship of cyanine tau aggregation inhibitors. J Med Chem. 2009 Jun 11;52(11):3539-47. Chemical & Physical Properties Melting Point 290ºC(dec.)(lit.) Molecular Formula C22H23IN2S2 Molecular Weight 506.46600 Exact Mass 506.03500 PSA 65.29000 LogP 2.41390 InChIKey SAEMBGFHGROQJZ-UHFFFAOYSA-M SMILES CCN1C(=CC(C)=Cc2sc3ccccc3[n+]2CC)Sc2ccccc21.[I-] |
| Use of | 3,3'-Diethyl-9-methylthiacarbocyanine iodide is a cyanine dye, also a tau aggregation inhibitor, with an IC50 value of 0.28 μM for tau. 3,3'-Diethyl-9-methylthiacarbocyanine iodide can cause misfunction of the microtubule cytoskeleton. 3,3'-Diethyl-9-methylthiacarbocyanine iodide can be used for researching Alzheimer's disease[1]. Properties Name (2Z)-3-ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)-2-methylprop-2-enylidene]-1,3-benzothiazole,iodide Synonym More Synonyms Biological Activity Description 3,3'-Diethyl-9-methylthiacarbocyanine iodide is a cyanine dye, also a tau aggregation inhibitor, with an IC50 value of 0.28 μM for tau. 3,3'-Diethyl-9-methylthiacarbocyanine iodide can cause misfunction of the microtubule cytoskeleton. 3,3'-Diethyl-9-methylthiacarbocyanine iodide can be used for researching Alzheimer's disease[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin Research Areas >> Neurological Disease IC50: 0.28 μM (tau)[1] References [1]. Chang E, et al. Structure-activity relationship of cyanine tau aggregation inhibitors. J Med Chem. 2009 Jun 11;52(11):3539-47. Chemical & Physical Properties Molecular Formula C22H23IN2S2 Exact Mass 506.03500 PSA 65.29000 LogP 2.41390 InChIKey SAEMBGFHGROQJZ-UHFFFAOYSA-M |
| Transport Info | Product name: 3,3'-diethyl-9-methylthiacarbocyanine iodide |
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