CAS Number2922-74-9
SynonymsMFCD00065990; disodium 2'-deoxyadenosine 5'-monophosphate; 5'-Adenylic acid, 2'-deoxy-, sodium salt (1:2); Disodium 2'-deoxy-5'-O-phosphonatoadenosine; EINECS 220-873-3
Molecular FormulaC10H12N5Na2O6P
Molecular Weight390.08
Purity≥95 (CP)%
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2922-74-9 |
| Catalog No. | 2A-9029195 |
| Chinese Name | 脱氧腺苷磷酸二钠 |
| Synonyms | MFCD00065990; disodium 2'-deoxyadenosine 5'-monophosphate; 5'-Adenylic acid, 2'-deoxy-, sodium salt (1:2); Disodium 2'-deoxy-5'-O-phosphonatoadenosine; EINECS 220-873-3 |
| Molecular Formula | C10H12N5Na2O6P |
| Molecular Weight | 390.08 |
| Purity | ≥95 (CP) |
| Appearance | solid |
| Water Solubility | H2O: 50 mg/mL, clear, colorless |
| Storage Condition | −20°C |
| Application | 2′-Deoxyadenosine 5′-monophosphate disodium is a nucleic acid AMP derivative, the deoxyribonucleic acid found in DNA. Disodium 2′-deoxyadenosine 5′-monophosphate can be used to study adenosine-based i |
| PubChem ID | 24894014 |
| MDL Number | MFCD08702946 |
| SMILES | [H][13C]1([H])[13C@]([H])(O)[13C@]([13CH2]OP(O[Na])(O[Na])=O)([H])O[13C@]1([15N]2[13CH]=[15N][13C]3=[13C]2[15N]=[13CH][15N]=[13C]3[15NH2])[H] |
| InChI | InChI=1S/C10H14N5O6P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1 |
| InChI Key | AYFGMFAEGVXUKY-VWZUFWLJSA-N |
| NACRES Code | NA.12 |
| UNSPSC | 41106305 |
| Hazard Symbols | transportation |
| MSDS | msds/29195_1_2922_74_9.pdf |
| Bioactivity | 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1]. Related Catalog Research Areas >> Metabolic Disease In Vitro 2′-Deoxyadenosine 5′-monophosphate (dAMP) is incorporated into Caco-2 cells in a time-dependent manner. The uptake of 2′-Deoxyadenosine 5′-monophosphate is increased with a drop in pH, suggesting that 2′-Deoxyadenosine 5′-monophosphate transport activity might be linked to the protons. 2′-Deoxyadenosine 5′-monophosphate uptake by Caco-2 cells is pH- and Na+-dependent[1]. References [1]. Katsuya Narumi, et al. Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP. PLoS One. 2019 Oct 21;14(10):e0223892. [2]. V Duarte, et al. Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine. Nucleic Acids Res. 1999 Jan 15;27(2):496-502. Chemical & Physical Properties Molecular Formula C10H12N5Na2O6P Molecular Weight 375.185 Exact Mass 375.032074 PSA 181.31000 LogP 0.62380 InChIKey AYFGMFAEGVXUKY-VWZUFWLJSA-N SMILES Nc1ncnc2c1ncn2C1CC(O)C(COP(=O)(O)O)O1.[Na] Storage condition −20°C Water Solubility H2O: 50 mg/mL, clear, colorless |
| Use of | 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1]. Properties Name 2'-Deoxyadenosine-5'-monophosphate disodium salt Synonym More Synonyms Biological Activity Description 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1]. Related Catalog Research Areas >> Metabolic Disease References [1]. Katsuya Narumi, et al. Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP. PLoS One. 2019 Oct 21;14(10):e0223892. [2]. V Duarte, et al. Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine. Nucleic Acids Res. 1999 Jan 15;27(2):496-502. Chemical & Physical Properties Molecular Formula C10H12N5Na2O6P Exact Mass 375.032074 PSA 181.31000 LogP 0.62380 InChIKey AYFGMFAEGVXUKY-VWZUFWLJSA-N |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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