![2-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide structure, CAS 2156-29-8](/structures/40000/2156-29-8.gif)
CAS Number2156-29-8
SynonymsD-308; 2-{2-[4-(dimethylamino)phenyl]ethenyl}-1-methylpyridinium iodide; 2-(4-(Dimethylamino)styryl)-N-methylpyridinium; MFCD00011980; o-DPD; 2-<4-(dimethylamino)styryl>-1-ethylpyridinium iodide; 2-(4-(dimethylamino)styryl)-1-methylpyridinium; (E)-2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide; 2-(4-DIMETHYLAMINOSTYRYL)-1-METHYLPYRIDINIUM IODIDE; 2-DI-1-ASP; EINECS 218-460-8; 1-METHYL-2-P-DIMETHYLAMINO-STYRYL-PYRIDINIUM-IODIDE
Molecular FormulaC16H19N2I1
Molecular Weight366.24
Purity98.00%
Density1.091g/cm3
Boiling Point397.8℃at 760 mmHg
Melting Point280ºC (dec.)(lit.)
Appearancered solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2156-29-8 |
| Catalog No. | 2A-9028070 |
| Chinese Name | 2-[4-(二甲氨基)苯乙烯基]-1-甲基吡啶碘 |
| Synonyms | D-308; 2-{2-[4-(dimethylamino)phenyl]ethenyl}-1-methylpyridinium iodide; 2-(4-(Dimethylamino)styryl)-N-methylpyridinium; MFCD00011980; o-DPD; 2-<4-(dimethylamino)styryl>-1-ethylpyridinium iodide; 2-(4-(dimethylamino)styryl)-1-methylpyridinium; (E)-2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide; 2-(4-DIMETHYLAMINOSTYRYL)-1-METHYLPYRIDINIUM IODIDE; 2-DI-1-ASP; EINECS 218-460-8; 1-METHYL-2-P-DIMETHYLAMINO-STYRYL-PYRIDINIUM-IODIDE |
| Molecular Formula | C16H19N2I1 |
| Molecular Weight | 366.24 |
| Purity | 98.00 |
| Density | 1.091g/cm3 |
| Boiling Point | 397.8℃at 760 mmHg |
| Melting Point | 280ºC (dec.)(lit.) |
| Appearance | red solid |
| Water Solubility | DMSO: soluble |
| Storage Condition | Store at room temperature in a cool and ventilated |
| Application | 2-Di-1-ASP (Compound 18a) is a monostyrene dye widely used as a mitochondrial stain of double-stranded DNA and as a groove-binding fluorescent probe. 2-Di-1-ASP is selective for G-quadruplexes (G4) an |
| PubChem ID | 3258194 |
| MDL Number | MFCD00011980 |
| SMILES | CN(C)c1ccc(C=Cc2cccc[n+]2C)cc1.[I-] |
| InChI | InChI=1S/C16H19N2.HI/c1-17(2)15-10-7-14(8-11-15)9-12-16-6-4-5-13-18(16)3;/h4-13H,1-3H3;1H/q+1;/p-1 |
| InChI Key | XPOIQAIBZGSIDD-UHFFFAOYSA-M |
| Hazard Symbols | transportation |
| MSDS | msds/28070_1_2156_29_8.pdf |
| Bioactivity | 2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro 2-Di-1-ASP (Compound 18a) displays significant fluorescence enhancements in the presence of G-quadruplex (G4) structures (up to 300-fold), and good selectivity with respect to double-stranded DNA. 2-Di-1-ASP shows fluorimetric selectivity for parallel G4-DNA forms (c-kit2, c-kit87up, c-myc)[1]. References [1]. Xie X, et al. Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries. Beilstein J Org Chem. 2019 Aug 6;15:1872-1889. Chemical & Physical Properties Density 1.091g/cm3 Boiling Point 397.8℃at 760 mmHg Melting Point 280ºC (dec.)(lit.) Molecular Formula C16H19IN2 Molecular Weight 366.24000 Flash Point 179.3℃ Exact Mass 366.05900 PSA 7.12000 Vapour Pressure 1.55E-06mmHg at 25°C Index of Refraction 1.668 InChIKey XPOIQAIBZGSIDD-UHFFFAOYSA-M SMILES CN(C)c1ccc(C=Cc2cccc[n+]2C)cc1.[I-] Water Solubility DMSO: soluble |
| Use of | 2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA[1]. Properties Articles32 Name 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide Synonym More Synonyms 2-di-1-asp Biological Activity Description 2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Xie X, et al. Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries. Beilstein J Org Chem. 2019 Aug 6;15:1872-1889. Chemical & Physical Properties Molecular Formula C16H19IN2 Exact Mass 366.05900 PSA 7.12000 Index of Refraction 1.668 InChIKey XPOIQAIBZGSIDD-UHFFFAOYSA-M Water Solubility DMSO: soluble |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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