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Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > Cholesteryl myristate
Cholesteryl myristate structure, CAS 1989-52-2

Cholesteryl myristate

CAS Number1989-52-2

SynonymsCholesterol=tetradecanoate; CHOLESTERYL TETRADODEDECANOATE; EINECS 217-867-8; Cholesteryl myristate; Cholest-5-en-3-yl myristate; Cholesterol Myristate; Cholestryl myristate; MFCD00014256; Myristic Acid Cholesterol Ester; O-myristoyl-cholesterol; cholesteryl tetradecanoate; Cholestryl myristic acid; Myristinsaeure-cholesterylester

Molecular FormulaC41H72O2

Molecular Weight597.02

Purity98.00%

Density0.95 g/cm3

Boiling Point630.7ºC at 760 mmHg

Melting Point84 °C

Flash Point

Appearancewhite powder

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-9027769 Purity: 98.00%
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Quality Control of [ 1989-52-2 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number1989-52-2
Catalog No.2A-9027769
Chinese Name豆蔻酸胆固醇酯
SynonymsCholesterol=tetradecanoate; CHOLESTERYL TETRADODEDECANOATE; EINECS 217-867-8; Cholesteryl myristate; Cholest-5-en-3-yl myristate; Cholesterol Myristate; Cholestryl myristate; MFCD00014256; Myristic Acid Cholesterol Ester; O-myristoyl-cholesterol; cholesteryl tetradecanoate; Cholestryl myristic acid; Myristinsaeure-cholesterylester
Molecular FormulaC41H72O2
Molecular Weight597.02
Purity98.00
Density0.95 g/cm3
Boiling Point630.7ºC at 760 mmHg
Melting Point84 °C
Appearancewhite powder
Storage ConditionSeal and store at -20ºC
ApplicationCholesterol myristate is a natural steroid found in traditional Chinese medicine.
PubChem ID3136537
MDL NumberMFCD00014256
SMILESCCCCCCCCCCCCCC(=O)OC1CCC2(C)C(=CCC3C2CCC2(C)C(C(C)CCCC(C)C)CCC32)C1
InChIInChI=1S/C41H72O2/c1-7-8-9-10-11-12-13-14-15-16-17-21-39(42)43-34-26-28-40(5)33(30-34)22-23-35-37-25-24-36(32(4)20-18-19-31(2)3)41(37,6)29-27-38(35)40/h22,31-32,34-38H,7-21,23-30H2,1-6H3
InChI KeySJDMTGSQPOFVLR-ZVMQTDSHSA-N
Hazard Symbolstransportation
MSDSmsds/27769_1_1989_52_2.pdf
BioactivityCholesterol myristate is a natural steroid present in traditional Chinese medicine. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Natural Products >> Steroids Target Human Endogenous Metabolite In Vitro Mesenchymal stem cells (MSCs) transfected by the Id1 promoter reporter construct, cholesterol myristate increases the activity of Id1 promoter. Cholesterol myristate inhibits the apoptosis of MSCs induced by serum-free. Cholesterol myristate increases the expression of Id1 and its target gene bcl-x/l in MSCs treated with serum-free. Moreover, noggin, a BMP antagonist, reduces the anti-apoptotic effects of cholesterol myristate[1]. Cholesterol myristate inhibits the apoptosis of PC12 cells induced in serum-free condition. Cholesterol myristate significantly increases the expression of BMP4, BMPRIA, p-Smad1/5/8, Id1 and its antiapoptotic target gene Bcl-xL in PC12 cells treated in serum-free condition[1]. Cell Assay MSCs are cultured with or without serum in 96-well plates and treated with cholesterol myristate in various concentrations (0, 30 and 300 μg/mL) for 3 days. Each sample is repeated in five independent wells and is incubated for 72 h. After incubation, 20 μL MTT (5 mg/mL) is added and the culture is incubated for a further 4 h. The culture medium is discarded and replaced with 150 μL DMSO. The absorbance at 490nm is measured[1]. References [1]. Chen DF, et al. Cholesterol myristate suppresses the apoptosis of mesenchymal stem cells via upregulation of inhibitor of differentiation. Steroids. 2010 Dec 12;75(13-14):1119-26. [2]. Chen DF, et al. BMP-Id pathway targeted by cholesterol myristate suppresses the apoptosis of PC12 cells. Brain Res. 2011 Jan 7;1367:33-42. Chemical & Physical Properties Density 0.95 g/cm3 Boiling Point 630.7ºC at 760 mmHg Melting Point 84 °C Molecular Formula C41H72O2 Molecular Weight 597.00900 Flash Point 334.8ºC Exact Mass 596.55300 PSA 26.30000 LogP 12.64070 Vapour Pressure 8.15E-16mmHg at 25°C Index of Refraction 1.506 InChIKey SJDMTGSQPOFVLR-ZVMQTDSHSA-N SMILES CCCCCCCCCCCCCC(=O)OC1CCC2(C)C(=CCC3C2CCC2(C)C(C(C)CCCC(C)C)CCC32)C1 Storage condition −20°C
Use ofCholesterol myristate is a natural steroid present in traditional Chinese medicine. Properties Name cholesteryl myristate Synonym More Synonyms Cholesterol myristate Biological Activity Description Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Natural Products >> Steroids Human Endogenous Metabolite References [1]. Chen DF, et al. Cholesterol myristate suppresses the apoptosis of mesenchymal stem cells via upregulation of inhibitor of differentiation. Steroids. 2010 Dec 12;75(13-14):1119-26. Chemical & Physical Properties Molecular Formula C41H72O2 Exact Mass 596.55300 PSA 26.30000 LogP 12.64070 Index of Refraction 1.506 InChIKey SJDMTGSQPOFVLR-ZVMQTDSHSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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