CAS Number1981-58-4
SynonymsMFCD00068333; Sodium sulfametazine; Sodium sulfamezathine; Bovibol; 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide; Sodium [(4-aminophenyl)sulfonyl](4,6-dimethylpyrimidin-2-yl)azanide; sulfamethazine sodium; 4-Amino-N-(4,6-dimethyl-2-pyrimidyl)benzenesulfonamide Sodium Salt; Sodium sulfamethiazine; sodium sulfamethazine; Benzenesulfonamide, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-, sodium salt (1:1); Sulfadimidine sodium; Sodium [(4-aminophenyl)sulfonyl](4,6-dimethyl-2-pyrimidinyl)azanide; sodium sulfadimidinato; sulphadimidine sodium; Sodium sulfamethamide; sulfamethazine sodium salt; Sodium sulphamezathine
Molecular FormulaC12H13N4O2SNa
Molecular Weight300.31
Purity≥98%
Density1.392g/cm3
Boiling Point526.2ºC at 760mmHg
Melting Point176ºC
Appearancepowder
EINECS217-840-0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1981-58-4 |
| Catalog No. | 2A-9027758 |
| Chinese Name | 磺胺二甲异嘧啶钠 |
| Synonyms | MFCD00068333; Sodium sulfametazine; Sodium sulfamezathine; Bovibol; 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide; Sodium [(4-aminophenyl)sulfonyl](4,6-dimethylpyrimidin-2-yl)azanide; sulfamethazine sodium; 4-Amino-N-(4,6-dimethyl-2-pyrimidyl)benzenesulfonamide Sodium Salt; Sodium sulfamethiazine; sodium sulfamethazine; Benzenesulfonamide, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-, sodium salt (1:1); Sulfadimidine sodium; Sodium [(4-aminophenyl)sulfonyl](4,6-dimethyl-2-pyrimidinyl)azanide; sodium sulfadimidinato; sulphadimidine sodium; Sodium sulfamethamide; sulfamethazine sodium salt; Sodium sulphamezathine |
| Molecular Formula | C12H13N4O2SNa |
| Molecular Weight | 300.31 |
| Purity | ≥98 |
| Density | 1.392g/cm3 |
| Boiling Point | 526.2ºC at 760mmHg |
| Melting Point | 176ºC |
| Appearance | powder |
| Water Solubility | H2O: soluble50mg/mL |
| Storage Condition | Sealed, store at 2 ºC -8 ºC |
| Application | Sulfamethazine sodium (Sulfadimidine sodium) is an antibacterial agent that is widely used in the treatment and prevention of various animal diseases (such as gastrointestinal and respiratory tract in |
| EINECS | 217-840-0 |
| HTC | 2935009090 |
| PubChem ID | 24899666 |
| MDL Number | MFCD00068333 |
| SMILES | [Na].Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1 |
| InChI | 1S/C12H14N4O2S.Na.H/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11;;/h3-7H,13H2,1-2H3,(H,14,15,16);; |
| InChI Key | WIVZAHIZHZEEOX-UHFFFAOYSA-N |
| NACRES Code | NA.85 |
| UNSPSC | 51284910 |
| Hazard Symbols | transportation |
| MSDS | msds/27758_1_1981_58_4.pdf |
| Bioactivity | Sulfamethazine sodium (Sulfadimidine sodium) is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections). In China and the European Commission, the maximum residue level for Sulfamethazine sodium in animal product is set at 100 µg/kg[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial Target Bacterial[1] In Vivo Sulfamethazine (80 mg/kg; intravenous injection; healthy female pigs) treatment significantly reduces α, β and AUC0->∞, significantly increases t1/2α, Vd and CIB, and upon a single intramuscular administration of 80 mg/kg of Sulfamethazine the absolute bioavailability in pigs is 1.01[1]. Animal Model: 19 healthy female pigs (6-week-old, 4.5-6.2 kg)[1] Dosage: 80 mg/kg Administration: Intravenous injection (Pharmacokinetic study) Result: The half-life in distribution phase is 0.23 h and half-lifes in eliminations phase is 9.8 h. α, β and the AUC0->∞ were significantly decreased and t1/2α, Vd and CIB were significantly increased, and the absolute bioavailability in pigs is 1.01. References [1]. VAN Poucke LSG, et al. Pharmacokinetics and Tissue Residues of Sulfathiazole and Sulfamethazine in Pigs. J Food Prot. 1994 Sep;57(9):796-801. [2]. Sheng Y J, et al. Production of chicken yolk IgY to sulfamethazine: comparison with rabbit antiserum IgG. Food and Agricultural Immunology. 2015, 26(3):305-316. Chemical & Physical Properties Density 1.392g/cm3 Boiling Point 526.2ºC at 760mmHg Melting Point 176ºC Molecular Formula C12H13N4NaO2S Molecular Weight 300.312 Flash Point 272.1ºC Exact Mass 300.065704 PSA 97.56000 LogP 2.99720 Appearance of Characters white to off-white Vapour Pressure 3.64E-11mmHg at 25°C InChIKey NGIVTUVVBWOTNT-UHFFFAOYSA-N SMILES Cc1cc(C)nc([N-]S(=O)(=O)c2ccc(N)cc2)n1.[Na+] Storage condition 2-8°C Water Solubility H2O: soluble50mg/mL |
| Use of | Sulfamethazine sodium (Sulfadimidine sodium) is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections). In China and the European Commission, the maximum residue level for Sulfamethazine sodium in animal product is set at 100 µg/kg[1][2]. Properties Name sodium,(4-aminophenyl)sulfonyl-(4,6-dimethylpyrimidin-2-yl)azanide Synonym More Synonyms Sulfamethazine sodium salt Biological Activity Description Sulfamethazine sodium (Sulfadimidine sodium) is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections). In China and the European Commission, the maximum residue level for Sulfamethazine sodium in animal product is set at 100 µg/kg[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial Bacterial[1] References [1]. VAN Poucke LSG, et al. Pharmacokinetics and Tissue Residues of Sulfathiazole and Sulfamethazine in Pigs. J Food Prot. 1994 Sep;57(9):796-801. [2]. Sheng Y J, et al. Production of chicken yolk IgY to sulfamethazine: comparison with rabbit antiserum IgG. Food and Agricultural Immunology. 2015, 26(3):305-316. Chemical & Physical Properties Molecular Formula C12H13N4NaO2S Exact Mass 300.065704 PSA 97.56000 LogP 2.99720 Appearance of Characters white to off-white InChIKey NGIVTUVVBWOTNT-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 35.0% |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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