2'-Methoxycinnamaldehyde structure, CAS 1504-74-1

2'-Methoxycinnamaldehyde

CAS Number1504-74-1

SynonymsMFCD00007001; 3-(2-Methoxyphenyl)acrylaldehyde; 2-Methoxycinnamaldehyde; (2E)-3-(2-Methoxyphenyl)acrylaldehyde; β-(o-Methoxyphenyl)acrolein; o-Methoxycinnamaldehyde; o-Methoxycinnamicaldehyde crystals; (2E)-3-(2-Methoxyphenyl)Prop-2-Enal; EINECS 216-131-3

Molecular FormulaCH3OC6H4CH=CHCHO

Molecular Weight162.19

Purity98.00%

Density1.1±0.1 g/cm3

Boiling Point334.8±0.0 °C at 760 mmHg

Melting Point44-48ºC

Flash Point

Appearanceyellow crystal

EINECS

MSDSChineseEnglish

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Cat. No.: 2A-9026941 Purity: 98.00%
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Quality Control of [ 1504-74-1 ] Purity: 98.00% SDS Specification MoL

Chemical & Physical Properties
CAS Number1504-74-1
Catalog No.2A-9026941
Chinese Name邻甲氧基肉桂醛
SynonymsMFCD00007001; 3-(2-Methoxyphenyl)acrylaldehyde; 2-Methoxycinnamaldehyde; (2E)-3-(2-Methoxyphenyl)acrylaldehyde; β-(o-Methoxyphenyl)acrolein; o-Methoxycinnamaldehyde; o-Methoxycinnamicaldehyde crystals; (2E)-3-(2-Methoxyphenyl)Prop-2-Enal; EINECS 216-131-3
Molecular FormulaCH3OC6H4CH=CHCHO
Molecular Weight162.19
Purity98.00
Density1.1±0.1 g/cm3
Boiling Point334.8±0.0 °C at 760 mmHg
Melting Point44-48ºC
Appearanceyellow crystal
Storage ConditionKeep the container sealed and stored in a cool, dr
Application2-Methoxycinnamaldehyde (o-Methoxycinnamaldehyde) is a natural compound in cinnamon that has anti-tumor activity. 2-Methoxycinnamaldehyde can inhibit cell proliferation and induce apoptosis by reducin
HTC2912499000
PubChem ID593914
SMILESCOc1ccccc1/C=C/C=O
InChIInChI=1S/C10H10O2/c1-12-10-7-3-2-5-9(10)6-4-8-11/h2-8H,1H3/b6-4+
InChI KeyInChIKey=KKVZAVRSVHUSPL-GQCTYLIASA-N
Hazard Symbolstransportation
Bioactivity2-Methoxycinnamaldehyde (o-Methoxycinnamaldehyde) is a natural compound of Cinnamomum cassia, with antitumor activity[1][2][3]. 2-Methoxycinnamaldehyde inhibits proliferation and induces apoptosis by mitochondrial membrane potential (ΔΨm) loss, activation of both caspase-3 and caspase-9[2]. 2-Methoxycinnamaldehyde effectively inhibits platelet-derived growth factor (PDGF)-induced HASMC migration[3]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [1]. Wong HY, et al. Cinnamomum verum Component 2-Methoxycinnamaldehyde: A Novel Anticancer Agent with Both Anti-Topoisomerase I and II Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo. Phytother Res. 2016 Feb;30(2):331-40. [2]. Liu YH, et al. Cinnamomum verum ingredient 2-methoxycinnamaldehyde: a new antiproliferative drug targeting topoisomerase I and II in human lung squamous cell carcinoma NCI-H520 cells. Eur J Cancer Prev. 2017 Jul;26(4):314-323. [3]. Jin YH, et al. 2-Methoxycinnamaldehyde inhibits the TNF-α-induced proliferation and migration of human aortic smooth muscle cells. Int J Mol Med. 2017 Jan;39(1):191-198. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 334.8±0.0 °C at 760 mmHg Melting Point 44-48ºC Molecular Formula C10H10O2 Molecular Weight 162.185 Flash Point 134.4±13.9 °C Exact Mass 162.068085 PSA 26.30000 LogP 2.13 Vapour Pressure 0.0±0.7 mmHg at 25°C Index of Refraction 1.559
Use of2-Methoxycinnamaldehyde (o-Methoxycinnamaldehyde) is a natural compound of Cinnamomum cassia, with antitumor activity[1][2][3]. 2-Methoxycinnamaldehyde inhibits proliferation and induces apoptosis by mitochondrial membrane potential (ΔΨm) loss, activation of both caspase-3 and caspase-9[2]. 2-Methoxycinnamaldehyde effectively inhibits platelet-derived growth factor (PDGF)-induced HASMC migration[3]. Properties Articles15 Name (E)-2-Methoxycinnamaldehyde Synonym More Synonyms o-Methoxycinnamaldehyde Biological Activity Description 2-Methoxycinnamaldehyde (o-Methoxycinnamaldehyde) is a natural compound of Cinnamomum cassia, with antitumor activity[1][2][3]. 2-Methoxycinnamaldehyde inhibits proliferation and induces apoptosis by mitochondrial membrane potential (ΔΨm) loss, activation of both caspase-3 and caspase-9[2]. 2-Methoxycinnamaldehyde effectively inhibits platelet-derived growth factor (PDGF)-induced HASMC migration[3]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [3]. Jin YH, et al. 2-Methoxycinnamaldehyde inhibits the TNF-α-induced proliferation and migration of human aortic smooth muscle cells. Int J Mol Med. 2017 Jan;39(1):191-198. Chemical & Physical Properties Molecular Formula C10H10O2 Exact Mass 162.068085 PSA 26.30000 Index of Refraction 1.559
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Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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