
CAS Number1504-74-1
SynonymsMFCD00007001; 3-(2-Methoxyphenyl)acrylaldehyde; 2-Methoxycinnamaldehyde; (2E)-3-(2-Methoxyphenyl)acrylaldehyde; β-(o-Methoxyphenyl)acrolein; o-Methoxycinnamaldehyde; o-Methoxycinnamicaldehyde crystals; (2E)-3-(2-Methoxyphenyl)Prop-2-Enal; EINECS 216-131-3
Molecular FormulaCH3OC6H4CH=CHCHO
Molecular Weight162.19
Purity98.00%
Density1.1±0.1 g/cm3
Boiling Point334.8±0.0 °C at 760 mmHg
Melting Point44-48ºC
Appearanceyellow crystal
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1504-74-1 |
| Catalog No. | 2A-9026941 |
| Chinese Name | 邻甲氧基肉桂醛 |
| Synonyms | MFCD00007001; 3-(2-Methoxyphenyl)acrylaldehyde; 2-Methoxycinnamaldehyde; (2E)-3-(2-Methoxyphenyl)acrylaldehyde; β-(o-Methoxyphenyl)acrolein; o-Methoxycinnamaldehyde; o-Methoxycinnamicaldehyde crystals; (2E)-3-(2-Methoxyphenyl)Prop-2-Enal; EINECS 216-131-3 |
| Molecular Formula | CH3OC6H4CH=CHCHO |
| Molecular Weight | 162.19 |
| Purity | 98.00 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 334.8±0.0 °C at 760 mmHg |
| Melting Point | 44-48ºC |
| Appearance | yellow crystal |
| Storage Condition | Keep the container sealed and stored in a cool, dr |
| Application | 2-Methoxycinnamaldehyde (o-Methoxycinnamaldehyde) is a natural compound in cinnamon that has anti-tumor activity. 2-Methoxycinnamaldehyde can inhibit cell proliferation and induce apoptosis by reducin |
| HTC | 2912499000 |
| PubChem ID | 593914 |
| SMILES | COc1ccccc1/C=C/C=O |
| InChI | InChI=1S/C10H10O2/c1-12-10-7-3-2-5-9(10)6-4-8-11/h2-8H,1H3/b6-4+ |
| InChI Key | InChIKey=KKVZAVRSVHUSPL-GQCTYLIASA-N |
| Hazard Symbols | transportation |
| Bioactivity | 2-Methoxycinnamaldehyde (o-Methoxycinnamaldehyde) is a natural compound of Cinnamomum cassia, with antitumor activity[1][2][3]. 2-Methoxycinnamaldehyde inhibits proliferation and induces apoptosis by mitochondrial membrane potential (ΔΨm) loss, activation of both caspase-3 and caspase-9[2]. 2-Methoxycinnamaldehyde effectively inhibits platelet-derived growth factor (PDGF)-induced HASMC migration[3]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [1]. Wong HY, et al. Cinnamomum verum Component 2-Methoxycinnamaldehyde: A Novel Anticancer Agent with Both Anti-Topoisomerase I and II Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo. Phytother Res. 2016 Feb;30(2):331-40. [2]. Liu YH, et al. Cinnamomum verum ingredient 2-methoxycinnamaldehyde: a new antiproliferative drug targeting topoisomerase I and II in human lung squamous cell carcinoma NCI-H520 cells. Eur J Cancer Prev. 2017 Jul;26(4):314-323. [3]. Jin YH, et al. 2-Methoxycinnamaldehyde inhibits the TNF-α-induced proliferation and migration of human aortic smooth muscle cells. Int J Mol Med. 2017 Jan;39(1):191-198. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 334.8±0.0 °C at 760 mmHg Melting Point 44-48ºC Molecular Formula C10H10O2 Molecular Weight 162.185 Flash Point 134.4±13.9 °C Exact Mass 162.068085 PSA 26.30000 LogP 2.13 Vapour Pressure 0.0±0.7 mmHg at 25°C Index of Refraction 1.559 |
| Use of | 2-Methoxycinnamaldehyde (o-Methoxycinnamaldehyde) is a natural compound of Cinnamomum cassia, with antitumor activity[1][2][3]. 2-Methoxycinnamaldehyde inhibits proliferation and induces apoptosis by mitochondrial membrane potential (ΔΨm) loss, activation of both caspase-3 and caspase-9[2]. 2-Methoxycinnamaldehyde effectively inhibits platelet-derived growth factor (PDGF)-induced HASMC migration[3]. Properties Articles15 Name (E)-2-Methoxycinnamaldehyde Synonym More Synonyms o-Methoxycinnamaldehyde Biological Activity Description 2-Methoxycinnamaldehyde (o-Methoxycinnamaldehyde) is a natural compound of Cinnamomum cassia, with antitumor activity[1][2][3]. 2-Methoxycinnamaldehyde inhibits proliferation and induces apoptosis by mitochondrial membrane potential (ΔΨm) loss, activation of both caspase-3 and caspase-9[2]. 2-Methoxycinnamaldehyde effectively inhibits platelet-derived growth factor (PDGF)-induced HASMC migration[3]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [3]. Jin YH, et al. 2-Methoxycinnamaldehyde inhibits the TNF-α-induced proliferation and migration of human aortic smooth muscle cells. Int J Mol Med. 2017 Jan;39(1):191-198. Chemical & Physical Properties Molecular Formula C10H10O2 Exact Mass 162.068085 PSA 26.30000 Index of Refraction 1.559 |
| Tax Rebate | 9.0% |
| Supervision | None. MFN tariff: 5.5%. Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Specialty & Botanical Ingredients | ||
|---|---|---|
| 7-Hydroxycoumarin-3-carboxylic acid | 779-27-1 | 2A-9025241 |
| 4-Hydroxycoumarin | 1076-38-6 | 2A-9026071 |
| Dihydrojasmone | 1128-08-1 | 2A-9026269 |
| Isocyclocitral | 1335-66-6 | 2A-9026717 |
| DL-Menthol | 1490-04-6 | 2A-9026920 |
| 4-Nitrocinnamaldehyde | 1734-79-8 | 2A-9027379 |
| Thymolphthalein Complexone | 1913-93-5 | 2A-9027676 |
| 4-Methoxycinnamaldehyde | 1963-36-6 | 2A-9027738 |
| 5,7-Dihydroxy-4-methylcoumarin | 2107-76-8 | 2A-9027998 |
| L-Menthol; Menthol Crystals | 2216-51-5 | 2A-9028164 |
| Browse all Specialty & Botanical Ingredients products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA