
CAS Number1185-57-5
SynonymsFerric; EINECS 214-686-6; Iron(3+) 2-hydroxy-1,2,3-propanetricarboxylate ammoniate (1:1:1); Ferricammoniumcitrae; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, ammonium iron(3+) salt (1:1:1); MFCD00013099; Ammonium iron(III) citrate; Ammonium Ferric Citrate; Ammoniumironcitrate; IRON AMMONIUM CITRATE; Citric acid iron ammonium; Amonium Iron(III) Citrate Supplement; Ironandammoniumcit-rate; AmmoniumFerricCitrateUsp
Molecular FormulaC6H8O7 ·xFe3+ · yNH3
Molecular Weight261.975
Purity98.00%
Density1.8 g/cm3 (20ºC)
Boiling Point197ºC
AppearanceLight yellowish brown to red solid with a faint ammonia odor
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1185-57-5 |
| Catalog No. | 2A-9026388 |
| Chinese Name | 柠檬酸铁铵 |
| Synonyms | Ferric; EINECS 214-686-6; Iron(3+) 2-hydroxy-1,2,3-propanetricarboxylate ammoniate (1:1:1); Ferricammoniumcitrae; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, ammonium iron(3+) salt (1:1:1); MFCD00013099; Ammonium iron(III) citrate; Ammonium Ferric Citrate; Ammoniumironcitrate; IRON AMMONIUM CITRATE; Citric acid iron ammonium; Amonium Iron(III) Citrate Supplement; Ironandammoniumcit-rate; AmmoniumFerricCitrateUsp |
| Molecular Formula | C6H8O7 ·xFe3+ · yNH3 |
| Molecular Weight | 261.975 |
| Purity | 98.00 |
| Density | 1.8 g/cm3 (20ºC) |
| Boiling Point | 197ºC |
| Appearance | Light yellowish brown to red solid with a faint ammonia odor |
| Water Solubility | 1200 g/L (20 ºC) |
| Storage Condition | Keep the container sealed and stored in a cool, dr |
| Application | Ferric ammonium(III) citrate (ferric ammonium citrate), a non-transferrin-bound physiological form of iron, induces intracellular iron overload, leading to ferroptosis [1]. Ferric ammonium (III) citra |
| HTC | 2918150000 |
| PubChem ID | 53790347 |
| SMILES | O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Fe+3].[Fe+3].[Fe+3].[NH4+].[NH4+].[NH4+] |
| InChI | InChI=1S/C6H8O7.Fe.H3N/c7-3(8)1-6(13,5(11)12)2-4(9)10;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;1H3/q;+3;/p-3 |
| InChI Key | AUALKMYBYGCYNY-UHFFFAOYSA-E |
| Bioactivity | Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis[1]. Ammonium iron(III) citrate can enhance protein production[2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Ferroptosis In Vitro Ammonium iron(III) citrate (Ammonium ferric citrate; 1, 5, 10, 15 mM; 24 hours) with 5 mM induces cell death in HT1080 cells. AML12 cells were highly resistant to Ammonium iron(III) citrate, as they maintained cell viability about 80%. Ammonium iron(III) citrate can be actively transported into cells by specific transporter[1]. Ammonium iron(III) citrate (6, 12, 18 mg/L) has a higher biomas for Chlorella vulgaris FSP-E (CV) in BG-11 medium with 12 mg/L and 18 mg/L[2]. References [1]. Shenglin Fang, et al. Effects of intracellular iron overload on cell death and identification of potent cell death inhibitors. Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303. [2]. Yu-Cheng Lai, et al. Towards protein production and application by using Chlorella species as circular economy. Bioresour Technol. 2019 Oct;289:121625. Chemical & Physical Properties Density 1.8 g/cm3 (20ºC) Boiling Point 197ºC Molecular Formula C6H8FeNO7 Molecular Weight 261.975 Exact Mass 261.965027 PSA 102.37000 InChIKey AUALKMYBYGCYNY-UHFFFAOYSA-E SMILES O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Fe+3].[Fe+3].[Fe+3].[NH4+].[NH4+].[NH4+] Water Solubility 1200 g/L (20 ºC) |
| Use of | Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis[1]. Ammonium iron(III) citrate can enhance protein production[2]. Properties Articles30 Name Ammonium ferric citrate Synonym More Synonyms Ferric ammonium citrate Biological Activity Description Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis[1]. Ammonium iron(III) citrate can enhance protein production[2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Ferroptosis References [1]. Shenglin Fang, et al. Effects of intracellular iron overload on cell death and identification of potent cell death inhibitors. Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303. [2]. Yu-Cheng Lai, et al. Towards protein production and application by using Chlorella species as circular economy. Bioresour Technol. 2019 Oct;289:121625. Chemical & Physical Properties Molecular Formula C6H8FeNO7 Exact Mass 261.965027 PSA 102.37000 InChIKey AUALKMYBYGCYNY-UHFFFAOYSA-E SMILES O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Fe+3].[Fe+3].[Fe+3].[NH4+].[NH4+].[NH4+] |
| Tax Rebate | 13.0% |
| Supervision | 4. Export license A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods x. Export license (processing trade) y. Export license (small-scale border trade) |
| Inspection | R. Imported food hygiene supervision and inspection S. Export food hygiene supervision and inspection N. Export commodity inspection |
| Transport Info | Product Name: Supervision Conditions 4. Export License A. Customs Clearance Form for Inbound Goods B. Customs Clearance Form for Outbound Goods x. Export License (Processing Trade) y. Export License (Border Small Trade) |
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