CAS Number658-48-0
SynonymsMFCD00004187; a-methyl-D-tyrosine; a-methyl-dl-p-tyrosine; EINECS 211-523-0; (-)-α-Methyl-D-tyrosine; α-Methyl-D-tyrosine
Molecular FormulaC10H14ClNO3
Molecular Weight231.681
Purity98.00%
Density1.3±0.1 g/cm3
Boiling Point383.7±32.0 °C at 760 mmHg
Melting Point>300ºC(lit.)
AppearanceOff-white fine powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 658-48-0 |
| Catalog No. | 2A-9024778 |
| Chinese Name | 消旋甲酪氨酸 |
| Synonyms | MFCD00004187; a-methyl-D-tyrosine; a-methyl-dl-p-tyrosine; EINECS 211-523-0; (-)-α-Methyl-D-tyrosine; α-Methyl-D-tyrosine |
| Molecular Formula | C10H14ClNO3 |
| Molecular Weight | 231.681 |
| Purity | 98.00 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 383.7±32.0 °C at 760 mmHg |
| Melting Point | >300ºC(lit.) |
| Appearance | Off-white fine powder |
| Storage Condition | −20°C |
| Application | Alpha-methyl-p-tyrosine is a competitive inhibitor of tyrosine hydroxylase, the enzyme that converts tyrosine to levodopa (DOPA). α-Methyl-p-tyrosine is an orally active inhibitor of catecholamine syn |
| HTC | 2922509090 |
| MDL Number | MFCD00136544 |
| SMILES | CC(N)(Cc1ccc(O)cc1)C(=O)O |
| InChI | InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)/t10-/m0/s1 |
| InChI Key | NHTGHBARYWONDQ-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| MSDS | msds/24778_1_658_48_0.pdf |
| Bioactivity | α-Methyl-p-tyrosine is a competitive inhibitor of the enzyme tyrosine hydroxylase, which converts tyrosine to Levodopa (DOPA). α-Methyl-p-tyrosine is an orally active inhibitor of catecholamine synthesis which inhibits the hydroxylation of tyrosine to DOPA[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others References [1]. R N Brogden, et al. alpha-Methyl-p-tyrosine: a review of its pharmacology and clinical use. Drugs. 1981 Feb;21(2):81-9. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 383.7±32.0 °C at 760 mmHg Melting Point >300ºC(lit.) Molecular Formula C10H13NO3 Molecular Weight 195.215 Flash Point 185.9±25.1 °C Exact Mass 195.089539 PSA 83.55000 LogP 0.73 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.600 InChIKey NHTGHBARYWONDQ-UHFFFAOYSA-N SMILES CC(N)(Cc1ccc(O)cc1)C(=O)O Storage condition −20°C |
| Use of | α-Methyl-p-tyrosine is a competitive inhibitor of the enzyme tyrosine hydroxylase, which converts tyrosine to Levodopa (DOPA). α-Methyl-p-tyrosine is an orally active inhibitor of catecholamine synthesis which inhibits the hydroxylation of tyrosine to DOPA[1]. Properties Articles45 Name (S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid Synonym More Synonyms a-methyl-D-tyrosine Biological Activity Description α-Methyl-p-tyrosine is a competitive inhibitor of the enzyme tyrosine hydroxylase, which converts tyrosine to Levodopa (DOPA). α-Methyl-p-tyrosine is an orally active inhibitor of catecholamine synthesis which inhibits the hydroxylation of tyrosine to DOPA[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others References [1]. R N Brogden, et al. alpha-Methyl-p-tyrosine: a review of its pharmacology and clinical use. Drugs. 1981 Feb;21(2):81-9. Chemical & Physical Properties Molecular Formula C10H13NO3 Exact Mass 195.089539 PSA 83.55000 Index of Refraction 1.600 InChIKey NHTGHBARYWONDQ-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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