CAS Number480-68-2
Synonyms5-nitro-2,4,6-pyrimidinetrione; EINECS 207-557-0; 5-Nitro-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Nitrobarbituric Acid Trihydrate; NITROBARBITURIC ACID; AURORA KA-3829; 5-nitro-barbituricaci; 5-nitropyrimidine-2,4,6(1H,3H,5H)-trione; Dilituric Acid Trihydrate; 5-Nitrobarbiuricacid; MFCD00006667; DILITURIC ACID; 5-NITRO-2,4,6-TRIHYDROXYPYRIMIDINE; 5-NitrobarbituricAcid
Molecular FormulaC4H3N3O5
Molecular Weight173.084
Purity98.00%
Density1.8±0.1 g/cm3
Boiling Point303.69°C
Melting Point180.5°C
AppearanceSolid;White to Orange to Green powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 480-68-2 |
| Catalog No. | 2A-9022147 |
| Chinese Name | 5-硝基巴比妥酸 |
| Synonyms | 5-nitro-2,4,6-pyrimidinetrione; EINECS 207-557-0; 5-Nitro-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Nitrobarbituric Acid Trihydrate; NITROBARBITURIC ACID; AURORA KA-3829; 5-nitro-barbituricaci; 5-nitropyrimidine-2,4,6(1H,3H,5H)-trione; Dilituric Acid Trihydrate; 5-Nitrobarbiuricacid; MFCD00006667; DILITURIC ACID; 5-NITRO-2,4,6-TRIHYDROXYPYRIMIDINE; 5-NitrobarbituricAcid |
| Molecular Formula | C4H3N3O5 |
| Molecular Weight | 173.084 |
| Purity | 98.00 |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 303.69°C |
| Melting Point | 180.5°C |
| Appearance | Solid;White to Orange to Green powder to crystal |
| Storage Condition | Store in a sealed container in a ventilated and dr |
| Application | 5-Nitrobarbituric acid is an inhibitor of herpes simplex virus type 1 (HSV-1) (IC50=1.7μM) [1]. |
| HTC | 2933540000 |
| SMILES | O=C1NC(=O)C([N+](=O)[O-])C(=O)N1 |
| InChI | InChI=1S/C4H3N3O5/c8-2-1(7(11)12)3(9)6-4(10)5-2/h1H,(H2,5,6,8,9,10) |
| InChI Key | ABICJYZKIYUWEE-UHFFFAOYSA-N |
| Bioactivity | 5-Nitrobarbituric acid is a herpes simplex virus type-1 (HSV-1) inhibitor (IC50=1.7 μM)[1]. Related Catalog Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection Research Areas >> Inflammation/Immunology Target HSV-1:1.7 μM (IC50) In Vitro 5-Nitrobarbituric acid can inhibit vero cell growth[1]. Cell Cytotoxicity Assay[1] Cell Line: Vero cells Concentration: 0.06-5 μM Incubation Time: 2 hours Result: Showed high cytotoxicity to vero cells. References [1]. J V de Julián-Ortiz, et al. Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds. J Med Chem. 1999 Aug 26;42(17):3308-14. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Boiling Point 303.69°C Melting Point 180.5°C Molecular Formula C4H3N3O5 Molecular Weight 173.084 Exact Mass 173.007263 PSA 121.09000 LogP -1.13 Index of Refraction 1.581 InChIKey ABICJYZKIYUWEE-UHFFFAOYSA-N SMILES O=C1NC(=O)C([N+](=O)[O-])C(=O)N1 |
| Use of | 5-Nitrobarbituric acid is a herpes simplex virus type-1 (HSV-1) inhibitor (IC50=1.7 μM)[1]. Properties Name 5-Nitrobarbituric acid Synonym More Synonyms 5-Nitrobarbituric acid Biological Activity Description 5-Nitrobarbituric acid is a herpes simplex virus type-1 (HSV-1) inhibitor (IC50=1.7 μM)[1]. Related Catalog Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection Research Areas >> Inflammation/Immunology HSV-1:1.7 μM (IC50) In Vitro 5-Nitrobarbituric acid can inhibit vero cell growth[1]. Cell Cytotoxicity Assay[1] Cell Line: Vero cells Concentration: 0.06-5 μM Incubation Time: 2 hours Result: Showed high cytotoxicity to vero cells. References [1]. J V de Julián-Ortiz, et al. Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds. J Med Chem. 1999 Aug 26;42(17):3308-14. Chemical & Physical Properties Molecular Formula C4H3N3O5 Exact Mass 173.007263 PSA 121.09000 LogP -1.13 Index of Refraction 1.581 InChIKey ABICJYZKIYUWEE-UHFFFAOYSA-N SMILES O=C1NC(=O)C([N+](=O)[O-])C(=O)N1 |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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