CAS Number475-38-7
Synonyms5,8-Dihydroxy-1,4-naphthalenedione; EINECS 207-495-4; MFCD00001685; 5,8-Dihydroxy-1,4-naphthoquinone; 5,8-dihydroxynaphthalene-1,4-dione; Naphthazarin
Molecular FormulaC10H6O4
Molecular Weight190.15
Purity98.00%
Density1.592g/cm3
Boiling Point498.2ºC at 760mmHg
Melting Point220-230 °C (lit.)
AppearanceDark purple to brown-black powder
EINECS207-495-4
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 475-38-7 |
| Catalog No. | 2A-9022106 |
| Chinese Name | 5,8-二羟基-1,4-萘醌 |
| Synonyms | 5,8-Dihydroxy-1,4-naphthalenedione; EINECS 207-495-4; MFCD00001685; 5,8-Dihydroxy-1,4-naphthoquinone; 5,8-dihydroxynaphthalene-1,4-dione; Naphthazarin |
| Molecular Formula | C10H6O4 |
| Molecular Weight | 190.15 |
| Purity | 98.00 |
| Density | 1.592g/cm3 |
| Boiling Point | 498.2ºC at 760mmHg |
| Melting Point | 220-230 °C (lit.) |
| Appearance | Dark purple to brown-black powder |
| Storage Condition | Store in a sealed container in a ventilated and dr |
| Application | Naphthazarin (DHNQ) is a naturally occurring compound that is effective through multiple cellular mechanisms, including oxidative stress, mitochondrial apoptosis-inducing factor (AIF) activation, micr |
| EINECS | 207-495-4 |
| HTC | 2914690090 |
| PubChem ID | 24864236 |
| MDL Number | MFCD00001685 |
| SMILES | Oc1ccc(O)c2C(=O)C=CC(=O)c12 |
| InChI | 1S/C10H6O4/c11-5-1-2-6(12)10-8(14)4-3-7(13)9(5)10/h1-4,11-12H |
| InChI Key | RQNVIKXOOKXAJQ-UHFFFAOYSA-N |
| Beilstein/REAXYS | 880561 |
| NACRES Code | NA.23 |
| UNSPSC | 12352103 |
| MSDS | msds/22106_1_475_38_7.pdf |
| Bioactivity | Naphthazarin (DHNQ) is a naturally occurring compound. Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis and has anti-tumor effects[1][2]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Neurological Disease References [1]. Seon Young Choi, et al. Naphthazarin has a protective effect on the 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine-induced Parkinson's disease model. J Neurosci Res. 2012 Sep;90(9):1842-9. [2]. Omar Aljanadi, et al. Stimulation of Suicidal Erythrocyte Death by Naphthazarin. Basic Clin Pharmacol Toxicol. 2015 Dec;117(6):369-74. Chemical & Physical Properties Density 1.592g/cm3 Boiling Point 498.2ºC at 760mmHg Melting Point 220-230 °C(lit.) Molecular Formula C10H6O4 Molecular Weight 190.15200 Flash Point 269.2ºC Exact Mass 190.02700 PSA 74.60000 LogP 1.03300 Vapour Pressure 1.51E-10mmHg at 25°C Index of Refraction 1.71 InChIKey RQNVIKXOOKXAJQ-UHFFFAOYSA-N SMILES O=C1C=CC(=O)c2c(O)ccc(O)c21 |
| Use of | Naphthazarin (DHNQ) is a naturally occurring compound. Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis and has anti-tumor effects[1][2]. Properties Articles32 Name naphthazarin Synonym More Synonyms Naphthazarin Biological Activity Description Naphthazarin (DHNQ) is a naturally occurring compound. Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis and has anti-tumor effects[1][2]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Neurological Disease References [1]. Seon Young Choi, et al. Naphthazarin has a protective effect on the 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine-induced Parkinson's disease model. J Neurosci Res. 2012 Sep;90(9):1842-9. [2]. Omar Aljanadi, et al. Stimulation of Suicidal Erythrocyte Death by Naphthazarin. Basic Clin Pharmacol Toxicol. 2015 Dec;117(6):369-74. Chemical & Physical Properties Molecular Formula C10H6O4 Exact Mass 190.02700 PSA 74.60000 LogP 1.03300 Index of Refraction 1.71 InChIKey RQNVIKXOOKXAJQ-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 75.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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