
CAS Number156-86-5
Synonyms(S)-2-Amino-6-guanidinohexanoic acid; N6-(Aminoiminomethyl)-L-lysine; H-HOARG-OH; Homoarginine; MFCD00237108; L-Homoarginine; N-Carbamimidoyl-L-lysine; N6-amidino-L-Lysine; N6-Carbamimidoyl-L-lysin; H-HAR-OH; H-HOMOARGININE; H-HOMOARG-OH; Homo-L-arginine; N6-carbamimidoyl-L-lysine; l-lysin
Molecular FormulaC7H16N4O2
Molecular Weight188.227
Purity98.00%
Density1.4±0.1 g/cm3
Boiling Point376.3±52.0 °C at 760 mmHg
AppearanceWhite crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 156-86-5 |
| Catalog No. | 2A-9021059 |
| Chinese Name | 高精氨酸 |
| Synonyms | (S)-2-Amino-6-guanidinohexanoic acid; N6-(Aminoiminomethyl)-L-lysine; H-HOARG-OH; Homoarginine; MFCD00237108; L-Homoarginine; N-Carbamimidoyl-L-lysine; N6-amidino-L-Lysine; N6-Carbamimidoyl-L-lysin; H-HAR-OH; H-HOMOARGININE; H-HOMOARG-OH; Homo-L-arginine; N6-carbamimidoyl-L-lysine; l-lysin |
| Molecular Formula | C7H16N4O2 |
| Molecular Weight | 188.227 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 376.3±52.0 °C at 760 mmHg |
| Appearance | White crystalline powder |
| Storage Condition | Store at RT. |
| Application | H-HoArg-OH, a homologue of arginine, is a potent inhibitor of alkaline phosphatase in human bone and liver. |
| HTC | 29152900 |
| SMILES | NC(N)=NCCCCC(N)C(=O)O |
| InChI | InChI=1S/C7H16N4O2/c8-5(6(12)13)3-1-2-4-11-7(9)10/h5H,1-4,8H2,(H,12,13)(H4,9,10,11)/t5-/m0/s1 |
| InChI Key | QUOGESRFPZDMMT-YFKPBYRVSA-N |
| MSDS | msds/21059_1_156_86_5.pdf |
| Bioactivity | H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase. Related Catalog Research Areas >> Metabolic Disease Natural Products >> Others Target Human Endogenous Metabolite Alkaline phosphatase In Vitro It is found that H-HoArg-OH (L-homoarginine), a homologue of arginine, is a strong inhibitor of human bone and liver alkaline phosphatase while it has virtually no effect on intestinal and placental alkaline phosphatases unlike H-HoArg-OH which inhibits intestinal and placental alkaline phosphatases but not the liver and bone enzymes. These four tissues mentioned are the major contributors to the serum alkaline phosphatase[1]. It is also indicated that low levels of the endogenous amino acid H-HoArg-OH are linked to cardiovascular disease[2]. References [1]. Fishman W, et al. L-homoarginine; an inhibitor of serum "bone and liver" alkaline phosphatase. Clin Chim Acta. 1970 Aug;29(2):339-41. [2]. Atzler D, et al. L-homoarginine and cardiovascular disease. Curr Opin Clin Nutr Metab Care. 2015 Jan;18(1):83-8. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 376.3±52.0 °C at 760 mmHg Molecular Formula C7H16N4O2 Molecular Weight 188.227 Flash Point 181.4±30.7 °C Exact Mass 188.127319 PSA 125.22000 LogP -1.86 Vapour Pressure 0.0±1.8 mmHg at 25°C Index of Refraction 1.587 InChIKey QUOGESRFPZDMMT-YFKPBYRVSA-N SMILES NC(N)=NCCCCC(N)C(=O)O Storage condition Store at RT. |
| Use of | H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase. Properties Name L-homoarginine Synonym More Synonyms Homoarginine Biological Activity Description H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase. Related Catalog Research Areas >> Metabolic Disease Natural Products >> Others Human Endogenous Metabolite Alkaline phosphatase In Vitro It is found that H-HoArg-OH (L-homoarginine), a homologue of arginine, is a strong inhibitor of human bone and liver alkaline phosphatase while it has virtually no effect on intestinal and placental alkaline phosphatases unlike H-HoArg-OH which inhibits intestinal and placental alkaline phosphatases but not the liver and bone enzymes. These four tissues mentioned are the major contributors to the serum alkaline phosphatase[1]. It is also indicated that low levels of the endogenous amino acid H-HoArg-OH are linked to cardiovascular disease[2]. References [1]. Fishman W, et al. L-homoarginine; an inhibitor of serum "bone and liver" alkaline phosphatase. Clin Chim Acta. 1970 Aug;29(2):339-41. [2]. Atzler D, et al. L-homoarginine and cardiovascular disease. Curr Opin Clin Nutr Metab Care. 2015 Jan;18(1):83-8. Chemical & Physical Properties Molecular Formula C7H16N4O2 Exact Mass 188.127319 PSA 125.22000 LogP -1.86 Index of Refraction 1.587 InChIKey QUOGESRFPZDMMT-YFKPBYRVSA-N SMILES NC(N)=NCCCCC(N)C(=O)O Storage condition Store at RT. |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Summary 2925290090 other imines and their derivatives; salts thereof. Supervision conditions:None. VAT: 17.0%. Tax rebate rate:9.0%. MFN tariff: 6.5%. General tariff:30.0% |
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