CAS Number147-24-0
Synonyms2-Diphenylmethoxy-N,N-dimethylethylamine Hydrochloride; 2-benzhydryloxy-N,N-dimethylethanamine,hydrochloride; 2-(Benzhydryloxy)-N,N-dimethylethylamine, hydrochloride; Benzhydramine HCl; Diphenhydramine hydrochloride; 2-(Benzhydryloxy)-N,N-dimethylethylamine Hydrochloride; Allergina; benzhydramine hydrochloride; Ethanamine, 2- (diphenylmethoxy)-N,N-dimethyl-, hydrochloride; 2-(Diphenylmethoxy)-N,N-dimethylethanamine hydrochloride; EINECS 205-687-2; Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (1:1); Ethylamine, 2- (diphenylmethoxy)-N,N-dimethyl-, hydrochloride; N,N-Dimethyl-2-(diphenylmethoxy)-ethylamine hydrochloride; Ethylamine, N,N-dimethyl-2-(diphenylmethoxy)-, hydrochloride; 2-(diphénylméthoxy)-N,N-diméthyléthanamine chlorhydrate; Benadryl; Sedopretten; 2-Diphenylmethox
Molecular FormulaC17H22ClNO
Molecular Weight291.82
Purity≥98 (HPLC)%
Density1.024g/cm3
Boiling Point343.7ºC at 760 mmHg
Melting Point168-172 °C
Appearancepowder
EINECS205-687-2
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 147-24-0 |
| Catalog No. | 2A-9020971 |
| Chinese Name | 盐酸苯海拉明 |
| Synonyms | 2-Diphenylmethoxy-N,N-dimethylethylamine Hydrochloride; 2-benzhydryloxy-N,N-dimethylethanamine,hydrochloride; 2-(Benzhydryloxy)-N,N-dimethylethylamine, hydrochloride; Benzhydramine HCl; Diphenhydramine hydrochloride; 2-(Benzhydryloxy)-N,N-dimethylethylamine Hydrochloride; Allergina; benzhydramine hydrochloride; Ethanamine, 2- (diphenylmethoxy)-N,N-dimethyl-, hydrochloride; 2-(Diphenylmethoxy)-N,N-dimethylethanamine hydrochloride; EINECS 205-687-2; Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (1:1); Ethylamine, 2- (diphenylmethoxy)-N,N-dimethyl-, hydrochloride; N,N-Dimethyl-2-(diphenylmethoxy)-ethylamine hydrochloride; Ethylamine, N,N-dimethyl-2-(diphenylmethoxy)-, hydrochloride; 2-(diphénylméthoxy)-N,N-diméthyléthanamine chlorhydrate; Benadryl; Sedopretten; 2-Diphenylmethox |
| Molecular Formula | C17H22ClNO |
| Molecular Weight | 291.82 |
| Purity | ≥98 (HPLC) |
| Density | 1.024g/cm3 |
| Boiling Point | 343.7ºC at 760 mmHg |
| Melting Point | 168-172 °C |
| Appearance | powder |
| Water Solubility | 1000 g/L |
| Storage Condition | Store in a dry and cool place. |
| Application | Diphenhydramine (Benadryl) hydrochloride is a histamine H1 antagonist. |
| EINECS | 205-687-2 |
| HTC | 2933990090 |
| PubChem ID | 24277771 |
| MDL Number | MFCD00012479 |
| SMILES | Cl[H].CN(C)CCOC(c1ccccc1)c2ccccc2 |
| InChI | 1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H |
| InChI Key | PCHPORCSPXIHLZ-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352116 |
| MSDS | msds/20971_1_147_24_0.pdf |
| Bioactivity | Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations.Target: Histamine H1 receptorDiphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects. Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. Related Catalog Signaling Pathways >> GPCR/G Protein >> Histamine Receptor Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology References [1]. Benadryl. From Wikipedia, the free encyclopedia Chemical & Physical Properties Density 1.024g/cm3 Boiling Point 343.7ºC at 760 mmHg Melting Point 168-172 °C Molecular Formula C17H22ClNO Molecular Weight 291.816 Flash Point 101.5ºC Exact Mass 291.138977 PSA 12.47000 LogP 4.15620 InChIKey PCHPORCSPXIHLZ-UHFFFAOYSA-N SMILES CN(C)CCOC(c1ccccc1)c1ccccc1.Cl Stability Stable, but slowly darkens upon exposure to light. Incompatible with strong oxidizing agents. Water Solubility 1000 g/L |
| Use of | Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations.Target: Histamine H1 receptorDiphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects. Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. Properties Articles49 Name diphenhydramine hydrochloride Synonym More Synonyms Diphenhydramine Hydrochloride Biological Activity Description Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations.Target: Histamine H1 receptorDiphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects. Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. Related Catalog Signaling Pathways >> GPCR/G Protein >> Histamine Receptor Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology References [1]. Benadryl. From Wikipedia, the free encyclopedia Chemical & Physical Properties Exact Mass 291.138977 PSA 12.47000 LogP 4.15620 InChIKey PCHPORCSPXIHLZ-UHFFFAOYSA-N Stability Stable, but slowly darkens upon exposure to light. Incompatible with strong oxidizing agents. |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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