CAS Number128-53-0
SynonymsN-ethylmaleimide; EINECS 204-892-4; n-ethyl-maleimid; MFCD00005509; 1-ethylmaleimide; N-ethyl-maleimide; N-ethylmaleic imide; ethvlmaleimide; n-ethvlmaleimide; 1-Ethyl-1H-pyrrole-2,5-dione; N-Ethylmaleinimid; Ethylmaleimide
Molecular FormulaC6H7NO2
Molecular Weight125.13
Purity≥99.0 (HPLC)%
Density1.2±0.1 g/cm3
Boiling Point210 °C (lit.)
Melting Point43-46 °C
Appearancewhite solid
EINECS204-892-4
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 128-53-0 |
| Catalog No. | 2A-9020611 |
| Chinese Name | N-乙基顺丁烯二酰亚胺 |
| Synonyms | N-ethylmaleimide; EINECS 204-892-4; n-ethyl-maleimid; MFCD00005509; 1-ethylmaleimide; N-ethyl-maleimide; N-ethylmaleic imide; ethvlmaleimide; n-ethvlmaleimide; 1-Ethyl-1H-pyrrole-2,5-dione; N-Ethylmaleinimid; Ethylmaleimide |
| Molecular Formula | C6H7NO2 |
| Molecular Weight | 125.13 |
| Purity | ≥99.0 (HPLC) |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 210 °C (lit.) |
| Melting Point | 43-46 °C |
| Appearance | white solid |
| Water Solubility | 1 g/L (20 ºC) |
| Storage Condition | 2-8°C |
| Packaging | II |
| Application | N-Ethylmaleimide (NEM) is a cysteine protease inhibitor. N-Ethylmaleimide specifically inhibits phosphate transport in mitochondria. |
| EINECS | 204-892-4 |
| HTC | 2925190090 |
| PubChem ID | 329747901 |
| MDL Number | MFCD00005509 |
| SMILES | CCN1C(=O)C=CC1=O |
| InChI | 1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3 |
| InChI Key | HDFGOPSGAURCEO-UHFFFAOYSA-N |
| Beilstein/REAXYS | 112448 |
| NACRES Code | NA.26 |
| UNSPSC | 12352209 |
| Hazard Symbols | 6.1 |
| MSDS | msds/20611_1_128_53_0.pdf |
| Bioactivity | N-Ethylmaleimide (NEM) is a cysteine protease inhibitor[1]. N-ethylmaleimide specific inhibits phosphate transport in mitochondria[2]. Related Catalog Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin Target Cysteine protease[1] References [1]. Wu KH, et al. Cys32 and His105 are the critical residues for the calcium-dependent cysteine proteolyticactivity of CvaB, an ATP-binding cassette transporter. J Biol Chem. 2004 Jan 9;279(2):901-9. [2]. Hatase O , et al. Specific inhibition of phosphate transport in mitochondria by N-ethylmaleimide. Journal of Bioenergetics, 1973, 5(1):1-15. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 210.0±9.0 °C at 760 mmHg Melting Point 43-46 °C(lit.) Molecular Formula C6H7NO2 Molecular Weight 125.13 Flash Point 73.3±0.0 °C Exact Mass 125.047676 PSA 37.38000 LogP 0.68 Vapour Pressure 0.2±0.4 mmHg at 25°C Index of Refraction 1.514 InChIKey HDFGOPSGAURCEO-UHFFFAOYSA-N SMILES CCN1C(=O)C=CC1=O Storage condition 2-8°C Stability Stable. Combustible. Incompatible with strong oxidizing agents. Refrigerate. Water Solubility 1 g/L (20 ºC) |
| Use of | N-Ethylmaleimide (NEM) is a cysteine protease inhibitor[1]. N-ethylmaleimide specific inhibits phosphate transport in mitochondria[2]. Properties Articles253 Name N-ethylmaleimide Synonym More Synonyms N-ethylmaleimide Biological Activity Description N-Ethylmaleimide (NEM) is a cysteine protease inhibitor[1]. N-ethylmaleimide specific inhibits phosphate transport in mitochondria[2]. Related Catalog Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin Cysteine protease[1] References [1]. Wu KH, et al. Cys32 and His105 are the critical residues for the calcium-dependent cysteine proteolyticactivity of CvaB, an ATP-binding cassette transporter. J Biol Chem. 2004 Jan 9;279(2):901-9. [2]. Hatase O , et al. Specific inhibition of phosphate transport in mitochondria by N-ethylmaleimide. Journal of Bioenergetics, 1973, 5(1):1-15. Chemical & Physical Properties Molecular Formula C6H7NO2 Exact Mass 125.047676 PSA 37.38000 Index of Refraction 1.514 InChIKey HDFGOPSGAURCEO-UHFFFAOYSA-N Stability Stable. Combustible. Incompatible with strong oxidizing agents. Refrigerate. |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 2928 International Maritime Transport Danger Regulations: 2928 International Air Transport Danger Regulations: 2928 14.2 United Nations shipping name European Land Transport Dangerous Regulations: TOXIC SOLID, CORROSIVE, ORGANIC, N.O.S. (N-Ethylmaleimide) IMDG Code: TOXIC SOLID, CORROSIVE, ORGANIC, N.O.S. (N-Ethylmaleimide) International air transport hazard regulations: Toxic solid, corrosive, organic, n.o.s. (N-Ethylmaleimide) 14.3 Transport hazard categories European land transport risk code: 6.1 (8) International sea transport risk code: 6.1 (8) International air transport risk code: 6.1 (8) 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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