CAS Number127-58-2
SynonymsEINECS 204-851-0; Sulfamerazin natrium; Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1); MFCD00068332; Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide; 2-Sulfanilamido-4-methylpyrimidine sodium salt; Solumedine; UNII-JOV4UJY07O; Solfamerazina sodica [DCIT]; Sodium sulfamerazine; sulfamerazine sodium; Soluble sulfamerazine; Sodium sulphamerazine; Sodium [(4-aminophenyl)sulfonyl](4-methylpyrimidin-2-yl)azanide; Sulfamerazine sodium salt; Sulfamerazine (sodium salt)
Molecular FormulaC11H11N4O2SNa
Molecular Weight286.29
Purity98.00%
Boiling Point519.1ºC at 760mmHg
Melting Point216-219 °C
EINECS204-851-0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 127-58-2 |
| Catalog No. | 2A-9020586 |
| Chinese Name | 4-氨基-N-(4-甲基-2-嘧啶基)苯磺酰胺 |
| Synonyms | EINECS 204-851-0; Sulfamerazin natrium; Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1); MFCD00068332; Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide; 2-Sulfanilamido-4-methylpyrimidine sodium salt; Solumedine; UNII-JOV4UJY07O; Solfamerazina sodica [DCIT]; Sodium sulfamerazine; sulfamerazine sodium; Soluble sulfamerazine; Sodium sulphamerazine; Sodium [(4-aminophenyl)sulfonyl](4-methylpyrimidin-2-yl)azanide; Sulfamerazine sodium salt; Sulfamerazine (sodium salt) |
| Molecular Formula | C11H11N4O2SNa |
| Molecular Weight | 286.29 |
| Purity | 98.00 |
| Boiling Point | 519.1ºC at 760mmHg |
| Melting Point | 216-219 °C |
| Storage Condition | 2-8℃ |
| Application | Sulfamerazine (RP-2632) sodium salt is a sulfonamide antibiotic. |
| EINECS | 204-851-0 |
| PubChem ID | 57654599 |
| MDL Number | MFCD00068332 |
| SMILES | [Na+].Cc1ccnc([N-]S(=O)(=O)c2ccc(N)cc2)n1 |
| InChI | 1S/C11H11N4O2S.Na/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10;/h2-7H,12H2,1H3;/q-1;+1 |
| InChI Key | BSFJGCCAXDCMOX-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/20586_1_127_58_2.pdf |
| Bioactivity | Sulfamerazine Sodium is a sulfonamide antibacterial.Target: AntibacterialSulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamerazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA [1]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. HALL, W.H. and W.W. SPINK, Sulfamerazine: clinical evaluation in 116 cases. Journal of the American Medical Association, 1943. 123(3): p. 125-131. Chemical & Physical Properties Boiling Point 519.1ºC at 760mmHg Melting Point 216-219 °C Molecular Formula C11H11N4NaO2S Molecular Weight 286.285 Flash Point 267.8ºC Exact Mass 286.050049 PSA 97.56000 LogP 2.68880 Vapour Pressure 7.03E-11mmHg at 25°C InChIKey BSFJGCCAXDCMOX-UHFFFAOYSA-N SMILES Cc1ccnc([N-]S(=O)(=O)c2ccc(N)cc2)n1.[Na+] Storage condition 2-8℃ |
| Use of | Sulfamerazine Sodium is a sulfonamide antibacterial.Target: AntibacterialSulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamerazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA [1]. Properties Name sodium,(4-aminophenyl)sulfonyl-(4-methylpyrimidin-2-yl)azanide Synonym More Synonyms sulfamerazine sodium Biological Activity Description Sulfamerazine Sodium is a sulfonamide antibacterial.Target: AntibacterialSulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamerazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA [1]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References Chemical & Physical Properties Molecular Formula C11H11N4NaO2S Exact Mass 286.050049 PSA 97.56000 LogP 2.68880 InChIKey BSFJGCCAXDCMOX-UHFFFAOYSA-N Storage condition 2-8℃ |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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