CAS Number603-45-2
Synonyms4-(p,p'-Dihydroxybenzhydrylidene)-2,5-cyclohexadien-1-one; Aurin No. 555; MFCD00001624; EINECS 210-041-8; 4-[bis(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one; Aurin; 4-<bis(4-hydroxyphenyl)methylene>-2,5-cyclohexadienone; rosolic acid; 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one; Corallin Spirit Soluble; 4,4'-Dihydroxyfuchsone; 4-(Bis(p-hydroxyphenyl)methylene)cyclohexa-2,5-dien-1-one; 4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one; Aurine; Corallin; p-Rosolic acid; Spirit Aurine; 4-[bis-(4-hydroxyphenyl)methylene]-cyclohexa-2,5-dienone; Rosalic Acid; CI 43800; Pararosolic Acid
Molecular FormulaC19H14O3
Molecular Weight290.31
Density1.3±0.1 g/cm3
Boiling Point543.0±50.0 °C at 760 mmHg
Melting Pointca. 308ºC (decomposes)
Appearancepowder
EINECS210-041-8
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 603-45-2 |
| Catalog No. | 2A-1202326 |
| Chinese Name | 玫红酸 |
| Synonyms | 4-(p,p'-Dihydroxybenzhydrylidene)-2,5-cyclohexadien-1-one; Aurin No. 555; MFCD00001624; EINECS 210-041-8; 4-[bis(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one; Aurin; 4-<bis(4-hydroxyphenyl)methylene>-2,5-cyclohexadienone; rosolic acid; 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one; Corallin Spirit Soluble; 4,4'-Dihydroxyfuchsone; 4-(Bis(p-hydroxyphenyl)methylene)cyclohexa-2,5-dien-1-one; 4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one; Aurine; Corallin; p-Rosolic acid; Spirit Aurine; 4-[bis-(4-hydroxyphenyl)methylene]-cyclohexa-2,5-dienone; Rosalic Acid; CI 43800; Pararosolic Acid |
| Molecular Formula | C19H14O3 |
| Molecular Weight | 290.31 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 543.0±50.0 °C at 760 mmHg |
| Melting Point | ca. 308ºC (decomposes) |
| Appearance | powder |
| Water Solubility | Solubility Practically insoluble in water, benzene |
| Storage Condition | 2. Storage Keep sealed |
| Application | Rosic acid is an activator of Nrf2 and its downstream targets. Rose acid increases the levels of angiogenic factors and reduces inflammation (TNF-α and IL-1β) and apoptosis markers (CXCL10 and CCL2). |
| EINECS | 210-041-8 |
| HTC | 2914501900 |
| PubChem ID | 24888536 |
| MDL Number | MFCD00001624 |
| SMILES | O=C(C=C1)C=CC1=C(C2=CC=C(O)C=C2)C3=CC=C(O)C=C3 |
| InChI | 1S/C19H14O3/c20-16-7-1-13(2-8-16)19(14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,20-21H |
| InChI Key | FYEHYMARPSSOBO-UHFFFAOYSA-N |
| Beilstein/REAXYS | 2055205 |
| NACRES Code | NA.47 |
| UNSPSC | 12171500 |
| Hazard Symbols | transportation |
| MSDS | msds/203336_1_603_45_2.pdf |
| Bioactivity | Rosolic Acid is an activator of Nrf2, as well as its downstream targets. Rosolic Acid increases the levels of angiogenic factors, decreases inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2). Rosolic Acid restores the function of pancreatic cells and protects endothelial cells (ECs) from endoplasmic reticulum stressed[1]. Related Catalog Signaling Pathways >> NF-κB >> Keap1-Nrf2 Research Areas >> Metabolic Disease References [1]. Amin KN, et al. Effect of Rosolic acid on endothelial dysfunction under ER stress in pancreatic microenvironment. Free Radic Res. 2021 Jun;55(6):698-713. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 543.0±50.0 °C at 760 mmHg Melting Point ca. 308ºC (decomposes) Molecular Formula C19H14O3 Molecular Weight 290.31 Flash Point 296.2±26.6 °C Exact Mass 290.094299 PSA 57.53000 LogP 3.15 Vapour Pressure 0.0±1.5 mmHg at 25°C Index of Refraction 1.691 InChIKey FYEHYMARPSSOBO-UHFFFAOYSA-N SMILES O=C1C=CC(=C(c2ccc(O)cc2)c2ccc(O)cc2)C=C1 Storage condition Store at room temperature. Water Solubility Solubility Practically insoluble in water, benzene; freely soluble in ethanol |
| Use of | Rosolic Acid is an activator of Nrf2, as well as its downstream targets. Rosolic Acid increases the levels of angiogenic factors, decreases inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2). Rosolic Acid restores the function of pancreatic cells and protects endothelial cells (ECs) from endoplasmic reticulum stressed[1]. Properties Articles15 Name 4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one Synonym More Synonyms Aurin Biological Activity Description Rosolic Acid is an activator of Nrf2, as well as its downstream targets. Rosolic Acid increases the levels of angiogenic factors, decreases inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2). Rosolic Acid restores the function of pancreatic cells and protects endothelial cells (ECs) from endoplasmic reticulum stressed[1]. Related Catalog Signaling Pathways >> NF-κB >> Keap1-Nrf2 Research Areas >> Metabolic Disease References [1]. Amin KN, et al. Effect of Rosolic acid on endothelial dysfunction under ER stress in pancreatic microenvironment. Free Radic Res. 2021 Jun;55(6):698-713. Chemical & Physical Properties Molecular Formula C19H14O3 Exact Mass 290.094299 PSA 57.53000 Index of Refraction 1.691 InChIKey FYEHYMARPSSOBO-UHFFFAOYSA-N Storage condition Store at room temperature. Water Solubility Solubility Practically insoluble in water, benzene; freely soluble in ethanol |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip. |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| [2,4,6-Trimethoxyphenyl]dicyclohexylphosphonium tetrafluoroborate | 1217887-12-1 | 2A-0202255 |
| 2-(2-(2-Bromoethoxy)ethoxy)ethyl methanesulfonate (Br-PEG3-MS) | 2702323-73-5 | 2A-0202271 |
| N-Desmethyl N-Nitroso bosutinib | 2A-0202315 | 2A-0202315 |
| (Des-Pro-NHEt9)-Leuprolide | 112642-14-5 | 2A-0202316 |
| Paramethodione | 115-67-3 | 2A-1202325 |
| Diethyl Safranine | 4569-86-2 | 2A-1202327 |
| 3-amino-7-(dimethylamino)-5-phenylphenazinium chloride | 2390-56-9 | 2A-1202328 |
| 4-(2-PYRIDYLAZO)RESORCINOL MONOSODIUM SALT HYDRATE | 16593-81-0 | 2A-1202331 |
| PARAROSANILINE ACETATE | 6035-94-5 | 2A-1202332 |
| nitrazine yellow | 1716-22-9 | 2A-1202333 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS