| Chemical & Physical Properties | |
|---|---|
| CAS Number | 671802-00-9 |
| Catalog No. | 2A-0200442 |
| Chinese Name | 3-(2-羟基乙氧基)丙酸叔丁酯 |
| Synonyms | MFCD22056310 |
| Molecular Formula | C9H18O4 |
| Molecular Weight | 190.23700 |
| Density | 1.031±0.06 g/cm3(Predicted) |
| Boiling Point | 274.0±15.0℃at 760 mmHg |
| Storage Condition | 2-8℃, dry, sealed, |
| Application | Hydroxy-PEG1-(CH2)2-Boc is a PROTAC linker and belongs to the PEG class. Can be used to synthesize PROTAC molecules. |
| SMILES | CC(C)(C)OC(=O)CCOCCO |
| InChI Key | ACWLDITVZGWIKA-UHFFFAOYSA-N |
| MSDS | msds/202355_1_671802_00_9.pdf |
| Bioactivity | Hydroxy-PEG1-(CH2)2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs Alkyl/ether In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Density 1.031±0.06 g/cm3(Predicted) Boiling Point 274.0±15.0℃at 760 mmHg Molecular Formula C9H18O4 Molecular Weight 190.23700 Exact Mass 190.12100 PSA 55.76000 LogP 0.72710 InChIKey ACWLDITVZGWIKA-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)CCOCCO |
| Use of | Hydroxy-PEG1-(CH2)2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 2-Methyl-2-propanyl 3-(2-hydroxyethoxy)propanoate Synonym More Synonyms Hydroxy-PEG1-(CH2)2-Boc Biological Activity Description Hydroxy-PEG1-(CH2)2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Alkyl/ether In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Molecular Formula C9H18O4 Exact Mass 190.12100 PSA 55.76000 LogP 0.72710 InChIKey ACWLDITVZGWIKA-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)CCOCCO |
| Transport Info | Product name: Hydroxy-PEG1-tert-butyl ester |
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