CAS Number14919-49-4
Synonyms3-Hydroxy-2-(4-hydroxyphenyl)chromone; 4'-Hydroxyflavonol; 3-hydroxy-2-(4-hydroxy-phenyl)-chromen-4-one; 3,4'-dihydroxyfavone; 3-Hydroxy-2-(4-hydroxy-phenyl)-chromen-4-on; 3,4'-dihydroxyfalvone; 3,4'-Dihydroxyflavone
Molecular FormulaC15H10O4
Molecular Weight254.24
Density1.472g/cm3
Boiling Point452.5ºC at 760mmHg
Melting Point275-276ºC
AppearanceSolid;White to Amber to Dark green powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 14919-49-4 |
| Catalog No. | 2A-2199515 |
| Chinese Name | 3,4'-二羟基黄酮 |
| Synonyms | 3-Hydroxy-2-(4-hydroxyphenyl)chromone; 4'-Hydroxyflavonol; 3-hydroxy-2-(4-hydroxy-phenyl)-chromen-4-one; 3,4'-dihydroxyfavone; 3-Hydroxy-2-(4-hydroxy-phenyl)-chromen-4-on; 3,4'-dihydroxyfalvone; 3,4'-Dihydroxyflavone |
| Molecular Formula | C15H10O4 |
| Molecular Weight | 254.24 |
| Density | 1.472g/cm3 |
| Boiling Point | 452.5ºC at 760mmHg |
| Melting Point | 275-276ºC |
| Appearance | Solid;White to Amber to Dark green powder to crystal |
| Storage Condition | Sealed at room temperature, protected from light, |
| Application | 3,4'-Dihydroxyflavone (3,4'-DHF) is an orally active flavonoid with antiviral activity, such as Influenza A virus. |
| HTC | 2914501900 |
| MDL Number | C15H10O4 |
| SMILES | O=c1c(O)c(-c2ccc(O)cc2)oc2ccccc12 |
| InChI Key | GPGOCTLAUAHUQO-UHFFFAOYSA-N |
| MSDS | msds/201498_1_14919_49_4.pdf |
| Bioactivity | 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1]. Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection In Vivo 3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1]. Animal Model: 3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1]. Dosage: 1 mg/kg per 30 μL. Administration: Oral administration daily for 5 days. Result: Significantly decreased virus titers and pathological changes in the lung and reduced body weight loss and death. References [1]. Hossain MK, et al. Antiviral activity of 3,4'-dihydroxyflavone on influenza a virus. J Microbiol. 2014 Jun;52(6):521-6. Chemical & Physical Properties Density 1.472g/cm3 Boiling Point 452.5ºC at 760mmHg Melting Point 275-276ºC Molecular Formula C15H10O4 Molecular Weight 254.24 Flash Point 175.7ºC Exact Mass 254.05800 PSA 70.67000 LogP 2.87120 Vapour Pressure 5.61E-09mmHg at 25°C Index of Refraction 1.712 InChIKey GPGOCTLAUAHUQO-UHFFFAOYSA-N SMILES O=c1c(O)c(-c2ccc(O)cc2)oc2ccccc12 |
| Use of | 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1]. Properties Name 3-hydroxy-2-(4-hydroxyphenyl)chromen-4-one Synonym More Synonyms 3,4'-Dihydroxyflavone Biological Activity Description 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1]. Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection References [1]. Hossain MK, et al. Antiviral activity of 3,4'-dihydroxyflavone on influenza a virus. J Microbiol. 2014 Jun;52(6):521-6. Chemical & Physical Properties Molecular Formula C15H10O4 Exact Mass 254.05800 PSA 70.67000 LogP 2.87120 Index of Refraction 1.712 InChIKey GPGOCTLAUAHUQO-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified 3,4'-dihydroxyflavone |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Ethanone, 2,2-dibromo-1-(4-methoxyphenyl)- | 13664-92-1 | 2A-1199502 |
| POLYSULFONE | 25135-51-7 | 2A-1199504 |
| 1,5-BIS(4-AMINOPHENOXY)PENTANE | 2391-56-2 | 2A-1199509 |
| 4-(Octadecyloxy)-1,3-benzenediamine | 155096-60-9 | 2A-1199511 |
| 3,4-Dichloroacetophenone | 2642-63-8 | 2A-2199514 |
| Aquafone P;SPPSU | 2A-1199516 | 2A-1199516 |
| Sulfonated Polyethersulfone | 2A-1199517 | 2A-1199517 |
| 3,4'-Dimethoxyflavone | 78933-14-9 | 2A-2199516 |
| 3,4-DINITROBENZOIC ACID | 5283-45-0 | 2A-2199518 |
| 3,5-Dichlorobenzoyl Nitrile | 99567-74-5 | 2A-2199519 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS