CAS Number491871-58-0
Synonyms2-oxo-4-phenyl-5H-furan-3-carbonitrile; 6-(5-Bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile; TCS PIM-1 1; 3-cyano-4-phenyl-2(5H)-furanone; 3-Cyano-4-phenyl-2(5H)-furanon; 3-Cyan-4-phenyl-2(5H)-furanon; 2-oxo-4-phenyl-2,5-dihydro-furan-3-carbonitrile; 2-oxo-4-phenyl-2,5-dihydro-3-furancarbonitrile; 3-cyano-4-phenyl-6-(3-bromo-6-hydroxyphenyl)-2-pyridone; 3-cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone; 6-(5-Bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydro-3-pyridinecarbonitrile
Molecular FormulaC18H11O2N2Br1
Molecular Weight367.2
Density1.6±0.1 g/cm3
Boiling Point592.6±50.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 491871-58-0 |
| Catalog No. | 2A-1198796 |
| Chinese Name | 3-氰基-4-苯基-6-(3-溴-6-羟基苯基)-2(1H)-吡啶酮 |
| Synonyms | 2-oxo-4-phenyl-5H-furan-3-carbonitrile; 6-(5-Bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile; TCS PIM-1 1; 3-cyano-4-phenyl-2(5H)-furanone; 3-Cyano-4-phenyl-2(5H)-furanon; 3-Cyan-4-phenyl-2(5H)-furanon; 2-oxo-4-phenyl-2,5-dihydro-furan-3-carbonitrile; 2-oxo-4-phenyl-2,5-dihydro-3-furancarbonitrile; 3-cyano-4-phenyl-6-(3-bromo-6-hydroxyphenyl)-2-pyridone; 3-cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone; 6-(5-Bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydro-3-pyridinecarbonitrile |
| Molecular Formula | C18H11O2N2Br1 |
| Molecular Weight | 367.2 |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 592.6±50.0 °C at 760 mmHg |
| Storage Condition | 2-8℃ |
| Application | TCS PIM-1 1 (sc-204330) is an ATP-competitive Pim-1 kinase inhibitor with an IC50 of 50nM and a higher inhibitory effect on Pim-2 and MEK1/MEK2. |
| MDL Number | MFCD00276275 |
| SMILES | N#Cc1c(-c2ccccc2)cc(-c2cc(Br)ccc2O)[nH]c1=O |
| InChI Key | SVSYJTYGPLVUOZ-UHFFFAOYSA-N |
| MSDS | msds/200738_1_491871_58_0.pdf |
| Transport Info | Product name: TCS PIM-1 1 |
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