| Chemical & Physical Properties | |
|---|---|
| CAS Number | 253688-62-9 |
| Catalog No. | 2A-1196855 |
| Chinese Name | Hydroxy desmethyl Bosentan |
| Synonyms | Hydroxy Desmethyl Bosentan |
| Molecular Formula | C26H27N5O7S |
| Molecular Weight | 553.58700 |
| Purity | 98.00 |
| Density | 1.426g/cm3 |
| Boiling Point | 782ºC at 760 mmHg |
| Application | Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolite. Produced in the liver by the cytochrome P450 enzymes CYP2C9 and CYP3A4. Bosentan is a potent endothelin-1 (ET) antagonist at ETA and ET |
| PubChem ID | 11619419 |
| SMILES | CC(C)(CO)c1ccc(S(=O)(=O)Nc2nc(-c3ncccn3)nc(OCCO)c2Oc2ccccc2O)cc1 |
| InChI | InChI=1S/C26H27N5O7S/c1-26(2,16-33)17-8-10-18(11-9-17)39(35,36)31-22-21(38-20-7-4-3-6-19(20)34)25(37-15-14-32)30-24(29-22)23-27-12-5-13-28-23/h3-13,32-34H,14-16H2,1-2H3,(H,29,30,31) |
| InChI Key | JXXCMZWROOURSZ-UHFFFAOYSA-N |
| Transport Info | Product name: Hydroxy desmethyl Bosentan |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 4-acetyl-N-{2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}-1-naphthamide | 1125812-54-5 | 2A-2196843 |
| 7-Methoxyl-1-Tetralone | 6386-19-7 | 2A-2196849 |
| Sarolaner | 1398609-39-6 | 2A-2196850 |
| 2-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-2,2-di(thiophen-2-yl)acetic Acid | 1207067-06-8 | 2A-1196853 |
| 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2''-bipyrimidin]-4-yl]-Benzenesulfonamide | 1257099-42-5 | 2A-1196854 |
| Phenol, 4-amino-2,3,6-trichloro- | 64981-10-8 | 2A-1196857 |
| L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[1-[(acetyloxy)methyl]-2-hydroxypropyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]- (9CI) | 133304-81-1 | 2A-1196858 |
| Perazine dimaleate | 14516-56-4 | 2A-1196861 |
| calcium dobesilate monohydrate | 117552-79-1 | 2A-1196862 |
| OPIORPHIN | 864084-88-8 | 2A-2196864 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS