![2-[2-(2-methoxyethoxy)ethoxy]ethylamine structure, CAS 74654-07-2](/structures/210000/198381_1_74654_07_2.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 74654-07-2 |
| Catalog No. | 2A-1196603 |
| Chinese Name | 2-(2-(2-甲氧基乙氧基)乙氧基)乙胺 |
| Synonyms | 2-[2-(2-methoxyethoxy)ethoxy]ethanamine; 2-[2-(2-methoxyethoxy)ethoxy]ethylamine |
| Molecular Formula | C7H17NO3 |
| Molecular Weight | 163.21 |
| Purity | ≥95 |
| Density | 0.978g/cm3 |
| Boiling Point | 223.9ºC at 760 mmHg |
| Appearance | liquid |
| Storage Condition | 2-8°C |
| Application | m-PEG3-Amine is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs). |
| EINECS | 277-952-0 |
| HTC | 2922199090 |
| PubChem ID | 10041900 |
| MDL Number | MFCD17215909 |
| SMILES | NCCOCCOCCOC |
| InChI | 1S/C7H17NO3/c1-9-4-5-11-7-6-10-3-2-8/h2-8H2,1H3 |
| InChI Key | OKUWOEKJQRUMBW-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352116 |
| MSDS | msds/198381_1_74654_07_2.pdf |
| Use of | m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Properties Name 2-(2-(2-Methoxyethoxy)ethoxy)ethanamine Synonym More Synonyms m-PEG3-Amine Biological Activity Description m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Nianhe Han, et al. The derivant of aplysiatoxin 10 and application thereof. CN106279352A. Chemical & Physical Properties Molecular Formula C7H17NO3 Exact Mass 163.12100 PSA 53.71000 LogP 0.32500 Index of Refraction 1.431 InChIKey OKUWOEKJQRUMBW-UHFFFAOYSA-N SMILES COCCOCCOCCN Safety Information Hazard Codes Xi HS Code 2922199090 Synthetic Route 2-[2-[2-(2-meth... CAS#:167221-50-3 m-PEG3-Amine CAS#:74654-07-2 Literature: Lowicki, Daniel; Huczynski, Adam; Brzezinski, Bogumil; Bartl, Franz Journal of Molecular Structure, 2011 , vol. 990, # 1-3 p. 121 - 131 m-PEG3-azide CAS#:74654-06-1 m-PEG3-Amine CAS#:74654-07-2 Literature: Schmidt, Manfred; Amstutz, Rene; Crass, Gerhard; Seebach, Dieter Chemische Berichte, 1980 , vol. 113, # 5 p. 1691 - 1707 m-PEG3-Tos CAS#:62921-74-8 m-PEG3-Amine CAS#:74654-07-2 Literature: Clerc, Jerome; Schellenberg, Barbara; Groll, Michael; Bachmann, Andre S.; Huber, Robert; Dudler, Robert; Kaiser, Markus European Journal of Organic Chemistry, 2010 , # 21 p. 3991 - 4003 Precursor & DownStream Precursor 6 CAS#:167221-50-3 2-[2-[2-(2-meth... CAS#:74654-06-1 m-PEG3-azide CAS#:62921-74-8 m-PEG3-Tos CAS#:112-35-6 DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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