| Chemical & Physical Properties | |
|---|---|
| CAS Number | 28821-35-4 |
| Catalog No. | 2A-1195846 |
| Chinese Name | HO-PEG15-OH |
| Synonyms | pentadecaethylene glycol; EINECS 249-258-8; 3,6,9,12,15,18,21,24,27,30,33,36,39,42-Tetradecaoxatetratetracontane-1,44-diol |
| Molecular Formula | C30H62O16 |
| Molecular Weight | 678.81 |
| Density | 1.116g/cm3 |
| Boiling Point | 687.9ºC at 760mmHg |
| Storage Condition | 2-8°C, sealed, dry |
| Application | HO-PEG15-OH is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules. |
| HTC | 2909499000 |
| PubChem ID | 29300832 |
| MDL Number | MFCD29079393 |
| SMILES | OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| InChI | InChI=1S/C30H62O16/c31-1-3-33-5-7-35-9-11-37-13-15-39-17-19-41-21-23-43-25-27-45-29-30-46-28-26-44-24-22-42-20-18-40-16-14-38-12-10-36-8-6-34-4-2-32/h31-32H,1-30H2 |
| InChI Key | OWTQQPNDSWCHOV-UHFFFAOYSA-N |
| MSDS | msds/197572_1_28821_35_4.pdf |
| Use of | HO-PEG15-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Synonym More Synonyms HO-PEG15-OH Biological Activity Description HO-PEG15-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C30H62O16 Exact Mass 678.40400 PSA 169.68000 Index of Refraction 1.466 InChIKey OWTQQPNDSWCHOV-UHFFFAOYSA-N SMILES OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO Safety Information HS Code 2909499000 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
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