| Chemical & Physical Properties | |
|---|---|
| CAS Number | 17598-96-8 |
| Catalog No. | 2A-1195844 |
| Chinese Name | HO-PEG13-OH |
| Synonyms | 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaoctatriacontane-1,38-diol; tridecaethylene glycol; EINECS 241-569-7 |
| Molecular Formula | C26H54O14 |
| Molecular Weight | 590.71 |
| Density | 1.116g/cm3 |
| Boiling Point | 631.6ºC at 760mmHg |
| Storage Condition | 2-8°C, sealed, dry |
| Application | HO-PEG13-OH is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules. |
| HTC | 2909499000 |
| PubChem ID | 10222191 |
| MDL Number | MFCD20926392 |
| SMILES | OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| InChI | InChI=1S/C26H54O14/c27-1-3-29-5-7-31-9-11-33-13-15-35-17-19-37-21-23-39-25-26-40-24-22-38-20-18-36-16-14-34-12-10-32-8-6-30-4-2-28/h27-28H,1-26H2 |
| InChI Key | AKWFJQNBHYVIPY-UHFFFAOYSA-N |
| MSDS | msds/197570_1_17598_96_8.pdf |
| Use of | HO-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Synonym More Synonyms HO-PEG13-OH Biological Activity Description HO-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C26H54O14 Exact Mass 590.35100 PSA 151.22000 Index of Refraction 1.465 InChIKey AKWFJQNBHYVIPY-UHFFFAOYSA-N SMILES OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO Safety Information HS Code 2909499000 Synthetic Route 1,42-diphenyl-2... CAS#:361543-06-8 HO-PEG13-OH CAS#:17598-96-8 Literature: Andrus, Merritt B.; Turner, Timothy M.; Updegraff, Emily P.; Sauna, Zuben E.; Ambudkar, Suresh V. Tetrahedron Letters, 2001 , vol. 42, # 23 p. 3819 - 3822 Pentaethylene g... CAS#:41024-91-3 HO-PEG13-OH CAS#:17598-96-8 Literature: Jayasuriya, Nimal; Bosak, Stanislav; Regen, Steven L. Journal of the American Chemical Society, 1990 , vol. 112, # 15 p. 5851 - 5854 THP-PEG4-OH CAS#:128660-97-9 HO-PEG13-OH CAS#:17598-96-8 Literature: Jayasuriya, Nimal; Bosak, Stanislav; Regen, Steven L. Journal of the American Chemical Society, 1990 , vol. 112, # 15 p. 5851 - 5854 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
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| 3,6,9,12,15,18,21,24,27,30,33,36,39,42-tetradecaoxatetratetracontane-1,44-diol | 28821-35-4 | 2A-1195846 |
| HO-PEG16-OH | 4669-05-0 | 2A-1195847 |
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| HO-PEG24-OH | 2243942-52-9 | 2A-1195849 |
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