CAS Number50-12-4
SynonymsPhenantoin; MEPHENYTOIN; mephenytoine; Methoin; Insulton; Triantoin; Mesantoin; 5-ethyl-3-methyl-5-phenylhydantoin; Sedantoinal; methyl Hydantoin; EINECS 200-012-8; MFCD00270025; Methylphenetoin; Epiazin; Sedantoin
Molecular FormulaC12H14N2O2
Molecular Weight218.25
Purity≥98 (HPLC)%
Density1.154g/cm3
Melting Point135-138 °C
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 50-12-4 |
| Catalog No. | 2A-2195609 |
| Chinese Name | 美芬妥因 |
| Synonyms | Phenantoin; MEPHENYTOIN; mephenytoine; Methoin; Insulton; Triantoin; Mesantoin; 5-ethyl-3-methyl-5-phenylhydantoin; Sedantoinal; methyl Hydantoin; EINECS 200-012-8; MFCD00270025; Methylphenetoin; Epiazin; Sedantoin |
| Molecular Formula | C12H14N2O2 |
| Molecular Weight | 218.25 |
| Purity | ≥98 (HPLC) |
| Density | 1.154g/cm3 |
| Melting Point | 135-138 °C |
| Appearance | solid |
| Storage Condition | 2-8°C |
| Application | Mephenytoin is an anticonvulsant and a substrate of CYP2C19 and CYP2B6. |
| HTC | 2933990090 |
| PubChem ID | 24724646 |
| MDL Number | MFCD00270025 |
| SMILES | CC[C@]1(NC(=O)N(C)C1=O)c2ccccc2 |
| InChI | 1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)/t12-/m0/s1 |
| InChI Key | GMHKMTDVRCWUDX-LBPRGKRZSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12161501 |
| Hazard Symbols | transportation |
| MSDS | msds/197316_1_50_12_4.pdf |
| Bioactivity | Mephenytoin, an anticonvulsant, is the CYP2C19 and CYP2B6 substrate[1]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Neurological Disease References [1]. Klaassen T, et al. Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity. Eur J Clin Pharmacol. 2008;64(4):387-398. [2]. Relling MV, et al. Mephenytoin phenotyping: lack of haematologic effect and timing of urine collections. Pharmacogenetics. 1991;1(1):42-49. Chemical & Physical Properties Density 1.154g/cm3 Melting Point 135-138ºC Molecular Formula C12H14N2O2 Molecular Weight 218.25200 Exact Mass 218.10600 PSA 49.41000 LogP 1.74020 Appearance of Characters solid | off-white InChIKey GMHKMTDVRCWUDX-UHFFFAOYSA-N SMILES CCC1(c2ccccc2)NC(=O)N(C)C1=O Storage condition 2-8°C |
| Use of | Properties Articles30 Name 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione Synonym More Synonyms Mephenytoin Biological Activity Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Neurological Disease References [2]. Relling MV, et al. Mephenytoin phenotyping: lack of haematologic effect and timing of urine collections. Pharmacogenetics. 1991;1(1):42-49. Chemical & Physical Properties Molecular Formula C12H14N2O2 Exact Mass 218.10600 PSA 49.41000 LogP 1.74020 Appearance of Characters solid | off-white InChIKey GMHKMTDVRCWUDX-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip. |
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