CAS Number62014-87-3
SynonymsHelichrysetin; 4',6'-dihydroxy-2',4-dimethoxychalcone; (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one; 6'-O-methylisosalipurpol
Molecular FormulaC16H14O5
Molecular Weight286.28
Purity≥90.0 (HPLC)%
Density1.4±0.1 g/cm3
Boiling Point532.0±50.0 °C at 760 mmHg
Appearancesolid
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 62014-87-3 |
| Catalog No. | 2A-1193914 |
| Chinese Name | 4,2',4'-三羟基-6'-甲氧基查耳酮 |
| Synonyms | Helichrysetin; 4',6'-dihydroxy-2',4-dimethoxychalcone; (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one; 6'-O-methylisosalipurpol |
| Molecular Formula | C16H14O5 |
| Molecular Weight | 286.28 |
| Purity | ≥90.0 (HPLC) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 532.0±50.0 °C at 760 mmHg |
| Appearance | solid |
| Storage Condition | 2-8℃, dry, sealed |
| Application | Helichrysetin, isolated from the flowers of Helichrysum odoratissimum, is an ID2 (DNA binding inhibitor 2) inhibitor that inhibits the formation of DCIS (ductal carcinoma in situ). Helichrysetin has a |
| HTC | 2914509090 |
| PubChem ID | 10588814 |
| MDL Number | MFCD12546716 |
| SMILES | O(C)c1c(c(cc(c1)O)O)C(=O)\C=C\c2ccc(cc2)O |
| InChI | 1S/C16H14O5/c1-21-15-9-12(18)8-14(20)16(15)13(19)7-4-10-2-5-11(17)6-3-10/h2-9,17-18,20H,1H3/b7-4+ |
| InChI Key | OWGUBYRKZATRIT-QPJJXVBHSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/195524_1_62014_87_3.pdf |
| Use of | Properties Name (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-2-prop en-1-one Synonym More Synonyms Helichrysetin Biological Activity Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [1]. Liu Y, et al. ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness. Breast Cancer Res Treat. 2019 May;175(1):77-90. [2]. Ho YF, et al. Induction of apoptosis and cell cycle blockade by helichrysetin in a549 human lung adenocarcinoma cells. Evid Based Complement Alternat Med. 2013;2013:857257. Chemical & Physical Properties Molecular Formula C16H14O5 Exact Mass 286.084137 PSA 86.99000 Index of Refraction 1.684 InChIKey OWGUBYRKZATRIT-QPJJXVBHSA-N Safety Information Hazard Codes Xi HS Code 2914509090 Synthetic Route Total: 1 Page (2E)-1-[2-metho... CAS#:1070781-94-0 Helichrysetin CAS#:62014-87-3 Literature: Aponte, Jose C.; Castillo, Denis; Estevez, Yannick; Gonzalez, German; Arevalo, Jorge; Hammond, Gerald B.; Sauvain, Michel Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 100 - 103 (E)-1-(2-methox... CAS#:1034276-39-5 Helichrysetin CAS#:62014-87-3 Literature: Vogel, Susanne; Ohmayer, Susanne; Brunner, Gabi; Heilmann, Joerg Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 8 p. 4286 - 4293 4-hydroxybenzal... CAS#:123-08-0 Helichrysetin CAS#:62014-87-3 Precursor & DownStream Precursor 2 CAS#:1070781-94-0 (2E)-1-[2-metho... CAS#:123-08-0 4-hydroxybenzal... DownStream 2 CAS#:3420-72-2 Flavokawain A CAS#:37308-75-1 Flavokawain C |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
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