| Chemical & Physical Properties | |
|---|---|
| CAS Number | 192185-72-1 |
| Catalog No. | 2A-1192587 |
| Chinese Name | Tipifarnib (R115777) |
| Synonyms | Zarnestra; S1453_Selleck; tipifarnib; Tipifarnib (Zarnestra) |
| Molecular Formula | C27H22Cl2N4O |
| Molecular Weight | 489.40 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 681.7±55.0 °C at 760 mmHg |
| Melting Point | 211-213ºC (dec.) |
| Appearance | Off-white to light beige solid |
| Storage Condition | -20?C Freezer |
| Application | Tipifarnib is a potent and specific inhibitor of farnesyltransferase (FTase) with an IC50 value of 0.6 nM. |
| PubChem ID | 329826003 |
| MDL Number | MFCD07772347 |
| SMILES | Cn1cncc1C(N)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C |
| InChI Key | PLHJCIYEEKOWNM-HHHXNRCGSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Transport Info | Product name: Tifafani |
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