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2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione structure, CAS 64567-60-8

2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione

CAS Number64567-60-8

Synonyms5-Hydroxythalidomide

Molecular FormulaC13H10O5N2

Molecular Weight274.23

Purity

Density1.611g/cm3

Boiling Point600ºC at 760mmHg

Melting Point

Flash Point

Appearance

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Cat. No.: 2A-1191899 Purity:
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Quality Control of [ 64567-60-8 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number64567-60-8
Catalog No.2A-1191899
Chinese NameThalidomide-5-OH
Synonyms5-Hydroxythalidomide
Molecular FormulaC13H10O5N2
Molecular Weight274.23
Density1.611g/cm3
Boiling Point600ºC at 760mmHg
Storage ConditionRoom temperature, inert gas storage
ApplicationThalidomide-5-OH is a Thalidomide-based cereblon ligand that recruits CRBN proteins. Thalidomide-5-OH can be connected to the target protein ligand through a linker to form a PROTAC molecule.
PubChem ID11765598
MDL NumberMFCD24386541
SMILESO=C1CCC(N2C(=O)c3ccc(O)cc3C2=O)C(=O)N1
InChIInChI=1S/C13H10N2O5/c16-6-1-2-7-8(5-6)13(20)15(12(7)19)9-3-4-10(17)14-11(9)18/h1-2,5,9,16H,3-4H2,(H,14,17,18)
InChI KeyLJBQRRQTZUJWRC-UHFFFAOYSA-N
Transport InfoProduct name: 2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione
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