CAS Number155558-32-0
Synonyms5-(1,4-Diazepan-1-ylsulfonyl)isoquinolin-1-ol hydrochloride (1:1); 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride hydrate; 5-(1,4-Diazepan-1-ylsulfonyl)-1(2H)-isoquinolinone hydrochloride (1:1); HA1100 Hydrochloride; HYDROXYFASUDIL; 1(2H)-Isoquinolinone, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1); Hydroxyfasudil monohydrochloride; HA1100; Hydroxy Fasudil Hydrochloride; Hydroxyfasudil (hydrochloride)
Molecular FormulaC14H18ClN3O3S
Molecular Weight307.37 (free base basis)
Melting Point>250ºC(dec.)
AppearanceWhite to light yellow powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 155558-32-0 |
| Catalog No. | 2A-1191721 |
| Chinese Name | HA 1100盐酸盐(羟基法舒地尔盐酸盐) |
| Synonyms | 5-(1,4-Diazepan-1-ylsulfonyl)isoquinolin-1-ol hydrochloride (1:1); 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride hydrate; 5-(1,4-Diazepan-1-ylsulfonyl)-1(2H)-isoquinolinone hydrochloride (1:1); HA1100 Hydrochloride; HYDROXYFASUDIL; 1(2H)-Isoquinolinone, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1); Hydroxyfasudil monohydrochloride; HA1100; Hydroxy Fasudil Hydrochloride; Hydroxyfasudil (hydrochloride) |
| Molecular Formula | C14H18ClN3O3S |
| Molecular Weight | 307.37 (free base basis) |
| Melting Point | >250ºC(dec.) |
| Appearance | White to light yellow powder to crystal |
| Storage Condition | -20℃, inert gas, dry, sealed |
| Application | Hydroxyfasudil hydrochloride is a ROCK inhibitor that inhibits the activities of ROCK1 and ROCK2 with IC50 values of 0.73 and 0.72 μM, respectively. |
| PubChem ID | 16464495 |
| MDL Number | MFCD06411567 |
| SMILES | Cl.O=c1[nH]ccc2c(S(=O)(=O)N3CCCNCC3)cccc12 |
| InChI | InChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H |
| InChI Key | XWWFOUVDVJGNNG-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Transport Info | Product name: HA 1100 hydrochloride (hydroxyfasudil hydrochloride) |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 3-Pentanone,1,2,4-trichloro-2-methyl- | 145556-04-3 | 2A-1191588 |
| METHYL 2-FORMYL-3-OXO-PROPIONATE | 50427-65-1 | 2A-1191703 |
| 3-Chloro-1H-pyrazol-5-aMine | 916211-79-5 | 2A-1191718 |
| DIMETHYL SUBERIMIDATE DIHYDROCHLORIDE | 34490-86-3 | 2A-1191719 |
| GSK872 | 1346546-69-7 | 2A-1191720 |
| METHYL (3R)-3-AMINO-3-(4-CHLOROPHENYL)PROPANOATE | 283159-92-2 | 2A-1191722 |
| N-Pyrazinylthiourea | 31437-05-5 | 2A-1191723 |
| TAK-659 | 1312691-33-0 | 2A-1191724 |
| Toxoflavin | 84-82-2 | 2A-1191725 |
| 3-(5-fluoro-2-Methylphenyl)-3-Methylbutanoic acid | 849353-56-6 | 2A-1191727 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS