CAS Number6665-67-4
Synonyms4',5-Dihydroxyflavone; 5-Hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 4',5-dihydroxy flavone; 5,4'-Dihydroxyflavone
Molecular FormulaC15H10O4
Molecular Weight254.24
Density1.4±0.1 g/cm3
Boiling Point486.0±45.0 °C at 760 mmHg
Melting Point239-240ºC
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6665-67-4 |
| Catalog No. | 2A-1190599 |
| Chinese Name | 5,4'-二羟基黄酮 |
| Synonyms | 4',5-Dihydroxyflavone; 5-Hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 4',5-dihydroxy flavone; 5,4'-Dihydroxyflavone |
| Molecular Formula | C15H10O4 |
| Molecular Weight | 254.24 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 486.0±45.0 °C at 760 mmHg |
| Melting Point | 239-240ºC |
| Appearance | powder |
| Storage Condition | 2-8℃ |
| Application | 4',5-Dihydroxyflavone is an inhibitor of soybean LOX-1/α-glucosidase. Its Ki value for soybean LOX-1 is 102.6 μM and its IC50 value for yeast α-glucosidase is 66 μM. |
| HTC | 2914501900 |
| PubChem ID | 6190744 |
| MDL Number | C15H10O4 |
| SMILES | O=c1cc(-c2ccc(O)cc2)oc2cccc(O)c12 |
| InChI | InChI=1S/C15H10O4/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,16-17H |
| InChI Key | OKRNDQLCMXUCGG-UHFFFAOYSA-N |
| Use of | 4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase. Properties Name 5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one Synonym More Synonyms 4',5-Dihydroxyflavone Biological Activity Description 4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase Research Areas >> Others Ki: 102.6 μM (LOX-1)[1]. IC50: 66 μM (α-glucosidase)[2]. References Chemical & Physical Properties Molecular Formula C15H10O4 Exact Mass 254.057907 PSA 70.67000 Index of Refraction 1.699 InChIKey OKRNDQLCMXUCGG-UHFFFAOYSA-N Storage condition 2-8℃ Safety Information HS Code 2914501900 Synthetic Route 2,6-Dihydroxyac... 4',5-Dihydr... Literature: Journal of Organic Chemistry, , vol. 56, # 16 p. 4884 - 4887 2-Iodo-1,3-benz... 41046-67-7 4',5-Dihydr... Literature: Acta Chemica Scandinavica, , vol. 48, # 1 p. 61 - 67 4-(5-tributylst... 141993-06-8 4',5-Dihydr... Literature: Acta Chemica Scandinavica, , vol. 48, # 1 p. 61 - 67 Precursor & DownStream Precursor 8 CAS#:699-83-2 2,6-Dihydroxyac... CAS#:41046-67-7 2-Iodo-1,3-benz... CAS#:141993-06-8 4-(5-tributylst... CAS#:133642-20-3 4-(tert-butyldi... DownStream 1 CAS#:6665-72-1 5-Hydroxy-2-(4-... |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Summary 2914501900 other ketone-phenols. Supervision conditions:None. VAT: 17.0%. Tax rebate rate:9.0%. MFN tariff:5.5%. General tariff:30.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 2',4'-Dihydroxy flavone | 170310-00-6 | 2A-1190594 |
| 3,2'-Dihydroxy flavone (2'-Hydroxyflavonol) | 6068-76-4 | 2A-1190595 |
| 3',4'-Dihydroxy-alpha-Naptho flavone | 2A-1190596 | 2A-1190596 |
| 3,6-Dihydroxy flavone | 108238-41-1 | 2A-1190597 |
| 3,7-Dihydroxy-3',4'-dimethoxy flavone | 93322-61-3 | 2A-1190598 |
| 5,6-Dihydroxy flavone | 6665-66-3 | 2A-1190600 |
| 6,7-Dihydroxy flavone | 38183-04-9 | 2A-1190601 |
| 7,2'-Dihydroxy flavone | 62252-07-7 | 2A-1190602 |
| 2',3'-Dimethoxy flavone | 2554-84-9 | 2A-1190603 |
| 2',4'-Dimethoxy-6-methyl flavanol | 2A-1190604 | 2A-1190604 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS