CAS Number108238-41-1
Synonyms3,6-dihydroxy-flavone; 2-phenyl-3,6-dihydroxy-4-benzopyrone; MFCD00143082; 3,6-dihydroxy-2-phenyl-4-benzopyrone; 6-Hydroxyflavonol
Molecular FormulaC15H10O4
Molecular Weight254.24
Density1.472g/cm3
Boiling Point477.1ºC at 760 mmHg
Melting Point231-234ºC
AppearanceSolid;White to Orange to Green powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 108238-41-1 |
| Catalog No. | 2A-1190597 |
| Chinese Name | 3,6-二羟基黄酮 |
| Synonyms | 3,6-dihydroxy-flavone; 2-phenyl-3,6-dihydroxy-4-benzopyrone; MFCD00143082; 3,6-dihydroxy-2-phenyl-4-benzopyrone; 6-Hydroxyflavonol |
| Molecular Formula | C15H10O4 |
| Molecular Weight | 254.24 |
| Density | 1.472g/cm3 |
| Boiling Point | 477.1ºC at 760 mmHg |
| Melting Point | 231-234ºC |
| Appearance | Solid;White to Orange to Green powder to crystal |
| Water Solubility | Soluble in water. |
| Storage Condition | Store airtight in a cool, dry warehouse. Keep away |
| Application | 3,6-Dihydroxyflavone is an anticancer agent. 3,6-Dihydroxyflavone reduces cell viability in a dose- and time-dependent manner and induces apoptosis by activating the caspase cascade and cleaving polyA |
| HTC | 2914400090 |
| PubChem ID | 5216682 |
| MDL Number | MFCD00143082 |
| SMILES | O=c1c(O)c(-c2ccccc2)oc2ccc(O)cc12 |
| InChI | InChI=1S/C15H10O4/c16-10-6-7-12-11(8-10)13(17)14(18)15(19-12)9-4-2-1-3-5-9/h1-8,16,18H |
| InChI Key | XHLOLFKZCUCROE-UHFFFAOYSA-N |
| Bioactivity | 3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [1]. Chang H, et al. 3,6-Dihydroxyflavone induces apoptosis in leukemia HL-60 cell via reactive oxygen species-mediated p38 MAPK/JNK pathway. Eur J Pharmacol. 2010;648(1-3):31-38. Chemical & Physical Properties Density 1.472g/cm3 Boiling Point 477.1ºC at 760 mmHg Melting Point 231-234ºC Molecular Formula C15H10O4 Molecular Weight 254.24 Flash Point 186.2ºC Exact Mass 254.05800 PSA 70.67000 LogP 2.87120 Vapour Pressure 6.55E-10mmHg at 25°C Index of Refraction 1.712 InChIKey XHLOLFKZCUCROE-UHFFFAOYSA-N SMILES O=c1c(O)c(-c2ccccc2)oc2ccc(O)cc12 Water Solubility Soluble in water. |
| Use of | 3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation[1]. Properties Name 3,6-dihydroxy-2-phenylchromen-4-one Synonym More Synonyms 3,6-Dihydroxyflavone Biological Activity Description 3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References Chemical & Physical Properties Molecular Formula C15H10O4 Exact Mass 254.05800 PSA 70.67000 LogP 2.87120 Index of Refraction 1.712 InChIKey XHLOLFKZCUCROE-UHFFFAOYSA-N Water Solubility Soluble in water. |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Summary 2914400090 other ketone-alcohols and ketone-aldehydes. Supervision conditions:None. VAT: 17.0%. Tax rebate rate:9.0%. MFN tariff:5.5%. General tariff:30.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 5,2',3'-Trimethoxy flavanone | 2A-1190592 | 2A-1190592 |
| 6,2',3'-Trimethoxy flavanone | 2A-1190593 | 2A-1190593 |
| 2',4'-Dihydroxy flavone | 170310-00-6 | 2A-1190594 |
| 3,2'-Dihydroxy flavone (2'-Hydroxyflavonol) | 6068-76-4 | 2A-1190595 |
| 3',4'-Dihydroxy-alpha-Naptho flavone | 2A-1190596 | 2A-1190596 |
| 3,7-Dihydroxy-3',4'-dimethoxy flavone | 93322-61-3 | 2A-1190598 |
| 5,4'-Dihydroxy flavone | 6665-67-4 | 2A-1190599 |
| 5,6-Dihydroxy flavone | 6665-66-3 | 2A-1190600 |
| 6,7-Dihydroxy flavone | 38183-04-9 | 2A-1190601 |
| 7,2'-Dihydroxy flavone | 62252-07-7 | 2A-1190602 |
| Browse all Specialty Chemicals products » | ||
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