![2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro- structure, CAS 2226664-93-1](/structures/210000/189637_1_2226664_93_1.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2226664-93-1 |
| Catalog No. | 2A-2188269 |
| Chinese Name | KY19382 |
| Molecular Formula | C17H11Cl2N3O2 |
| Molecular Weight | 360.2 |
| Appearance | solid |
| Storage Condition | 2-8°C, sealed, dry |
| Application | KY19382 is a highly effective oral dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10nm respectively. KY19382 activates Wnt/β-catenin signaling by inhibiting CXXC5-DVL interaction and GSK3 |
| PubChem ID | 438447987 |
| MDL Number | C17H11Cl2N3O2 |
| SMILES | CON=C1C(c2c(O)[nH]c3cc(Cl)c(Cl)cc23)=Nc2ccccc21 |
| InChI | InChI=1S/C17H11Cl2N3O2/c1-24-22-15-8-4-2-3-5-12(8)20-16(15)14-9-6-10(18)11(19)7-13(9)21-17(14)23/h2-7,21,23H,1H3/b22-15- |
| InChI Key | TVZDUDDLASVAOM-UHFFFAOYSA-N |
| Transport Info | Product name: KY19382 (A3051) |
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