CAS Number115-20-8
Synonyms2,2,2-Trichloroethanol; Trichloroethyl alcohol; EINECS 204-071-0; MFCD00004677; Trichloroethanol; Ethapon
Molecular FormulaCl3CCH2OH
Molecular Weight149.40
Purity≥99%
Density1.6±0.1 g/cm3
Boiling Point152-154 °C (lit.)
Melting Point17.8 °C (lit.)
AppearanceTransparent almost colorless liquid
EINECS204-071-0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 115-20-8 |
| Catalog No. | 2A-9018920 |
| Chinese Name | 2,2,2-三氯乙醇 |
| Synonyms | 2,2,2-Trichloroethanol; Trichloroethyl alcohol; EINECS 204-071-0; MFCD00004677; Trichloroethanol; Ethapon |
| Molecular Formula | Cl3CCH2OH |
| Molecular Weight | 149.40 |
| Purity | ≥99 |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 152-154 °C (lit.) |
| Melting Point | 17.8 °C (lit.) |
| Appearance | Transparent almost colorless liquid |
| Storage Condition | Store in a cool, ventilated warehouse. Keep away f |
| Packaging | III |
| Application | 2,2,2-Trichloroethanol is the active form of the sedative-hypnotic chloral hydrate and an agonist of the non-classical K2P channels TREK-1 and TRAAK. |
| EINECS | 204-071-0 |
| HTC | 29055910 |
| PubChem ID | 24900284 |
| MDL Number | MFCD00004677 |
| SMILES | OCC(Cl)(Cl)Cl |
| InChI | 1S/C2H3Cl3O/c3-2(4,5)1-6/h6H,1H2 |
| InChI Key | KPWDGTGXUYRARH-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1697495 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/18920_1_115_20_8.pdf |
| Bioactivity | 2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. Related Catalog Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel In Vitro 2,2,2-trichloroethanol activates a nonclassical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery[1]. References [1]. Nikhil K Parelkar , et al. 2,2,2-trichloroethanol Activates a Nonclassical Potassium Channel in Cerebrovascular Smooth Muscle and Dilates the Middle Cerebral Artery. J Pharmacol Exp Ther. 2010 Mar;332(3):803-10. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 152.1±35.0 °C at 760 mmHg Melting Point 17.8 °C(lit.) Molecular Formula C2H3Cl3O Molecular Weight 149.404 Flash Point 45.8±25.9 °C Exact Mass 147.924942 PSA 20.23000 LogP 1.38 Vapour density 5.16 (vs air) Vapour Pressure 1.3±0.6 mmHg at 25°C Index of Refraction 1.499 InChIKey KPWDGTGXUYRARH-UHFFFAOYSA-N SMILES OCC(Cl)(Cl)Cl |
| Use of | 2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. Properties Articles33 Name 2,2,2-trichloroethanol Synonym More Synonyms Ethapon Biological Activity Description 2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. Related Catalog Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel In Vitro 2,2,2-trichloroethanol activates a nonclassical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery[1]. References [1]. Nikhil K Parelkar , et al. 2,2,2-trichloroethanol Activates a Nonclassical Potassium Channel in Cerebrovascular Smooth Muscle and Dilates the Middle Cerebral Artery. J Pharmacol Exp Ther. 2010 Mar;332(3):803-10. Chemical & Physical Properties Exact Mass 147.924942 PSA 20.23000 Vapour density 5.16 (vs air) Index of Refraction 1.499 InChIKey KPWDGTGXUYRARH-UHFFFAOYSA-N SMILES OCC(Cl)(Cl)Cl |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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