
CAS Number91809-67-5
Synonyms6-Carboxytetramethylrhodamine; 6-TAMRA; N,N,N',N'-Tetramethyl-6-carboxyrhodamine; 9-(2,5-Dicarboxyphenyl)-3,6-bis(dimethylamino)xanthylium; Xanthylium, 9-(2,4-dicarboxyphenyl)-3,6-bis(dimethylamino)-, inner salt; 2-[3,6-Bis(dimethylamino)-9-xantheniumyl]-5-carboxybenzoate
Molecular FormulaC25H22O5N2
Molecular Weight430.46
AppearanceDeep red to purple powder or crystal
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 91809-67-5 |
| Catalog No. | 2A-2187507 |
| Chinese Name | 6-羧基四甲基罗丹明 |
| Synonyms | 6-Carboxytetramethylrhodamine; 6-TAMRA; N,N,N',N'-Tetramethyl-6-carboxyrhodamine; 9-(2,5-Dicarboxyphenyl)-3,6-bis(dimethylamino)xanthylium; Xanthylium, 9-(2,4-dicarboxyphenyl)-3,6-bis(dimethylamino)-, inner salt; 2-[3,6-Bis(dimethylamino)-9-xantheniumyl]-5-carboxybenzoate |
| Molecular Formula | C25H22O5N2 |
| Molecular Weight | 430.46 |
| Appearance | Deep red to purple powder or crystal |
| Storage Condition | 2~8°C |
| Application | Tetramethylrhodamine (TMR, TRITC) is a fluorophore widely used in the preparation of fluorescent antibodies and avidin derivatives for immunohistochemistry. |
| PubChem ID | 3190723 |
| MDL Number | MFCD29477680 |
| SMILES | CN(C)c1ccc2c(-c3cc(C(=O)[O-])ccc3C(=O)O)c3ccc(=[N+](C)C)cc-3oc2c1 |
| InChI | InChI=1S/C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)20-11-14(24(28)29)5-8-17(20)25(30)31/h5-13H,1-4H3,(H-,28,29,30,31) |
| InChI Key | COCMHKNAGZHBDZ-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | Tetramethylrhodamine (TMR, TRITC) has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry. Under the name TAMRA, the carboxylic acid of 6-TAMRA has also achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others Chemical & Physical Properties Melting Point NA Molecular Formula C25H22N2O5 Molecular Weight 430.453 Exact Mass 430.152863 PSA 97.05000 LogP 3.72780 InChIKey COCMHKNAGZHBDZ-UHFFFAOYSA-N SMILES CN(C)c1ccc2c(-c3cc(C(=O)[O-])ccc3C(=O)O)c3ccc(=[N+](C)C)cc-3oc2c1 Storage condition 2~8°C |
| Use of | Tetramethylrhodamine (TMR, TRITC) has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry. Under the name TAMRA, the carboxylic acid of 6-TAMRA has also achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. Properties Articles20 Name 4-carboxy-3-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]benzoate Synonym More Synonyms 6-Carboxytetramethylrhodamine Biological Activity Description Tetramethylrhodamine (TMR, TRITC) has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry. Under the name TAMRA, the carboxylic acid of 6-TAMRA has also achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others Chemical & Physical Properties Molecular Formula C25H22N2O5 Exact Mass 430.152863 PSA 97.05000 LogP 3.72780 InChIKey COCMHKNAGZHBDZ-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 90.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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