IDX-184

Name: IDX-184
Brand: 2A Biotech
SKU: 2A-2187152

CAS Number1036915-08-8

SynonymsIDX184; 2'-C-methylguanosine-5'-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl-N-benzylphosphoramidate]

Molecular FormulaC25H35N6O9PS

Molecular Weight626.63

Cat. No.: 2A-2187152 Purity:

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Quality Control of [ 1036915-08-8 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	1036915-08-8
Catalog No.	2A-2187152
Chinese Name	IDX184
Synonyms	IDX184; 2'-C-methylguanosine-5'-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl-N-benzylphosphoramidate]
Molecular Formula	C25H35N6O9PS
Molecular Weight	626.63
Application	IDX184 is a potent, orally active HCV replication inhibitor. IDX184 potently inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3 nM).
PubChem ID	87460610
MDL Number	C25H35N6O9PS
SMILES	CC(C)(CO)C(=O)SCCOP(=O)(NCc1ccccc1)OCC1OC(n2cnc3c(=O)[nH]c(N)nc32)C(C)(O)C1O
InChI	InChI=1S/C25H35N6O9PS/c1-24(2,13-32)22(35)42-10-9-38-41(37,28-11-15-7-5-4-6-8-15)39-12-16-18(33)25(3,36)21(40-16)31-14-27-17-19(31)29-23(26)30-20(17)34/h4-8,14,16,18,21,32-33,36H,9-13H2,1-3H3,(H,28,37)(H3,26,29,30,34)/t16-,18-,21-,25-,41?/m1/s1
InChI Key	FGHMGRXAHIXTBM-TWFJNEQDSA-N
Transport Info	Product name: IDX184

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