| Chemical & Physical Properties | |
|---|---|
| CAS Number | 132834-56-1 |
| Catalog No. | 2A-3186873 |
| Chinese Name | 1-(6-氯-5-(三氟甲基)吡啶-2-基)哌嗪 |
| Synonyms | MFCD00892750 |
| Molecular Formula | C10H11N3Cl1F3 |
| Molecular Weight | 265.67 |
| Density | 1.454g/cm3 |
| Boiling Point | 286.004ºC at 760 mmHg |
| Storage Condition | 2-8°C, protected from light, stored in inert gas |
| Application | Org-12962 is a selective, orally active 5-HT2C receptor agonist with a pEC50 value of 7.01. Org-12962 also has high potency on 5-HT2A and 5-HT2B receptors, with pEC50 of 6.38 and 6.28 respectively. Or |
| HTC | 2933990090 |
| PubChem ID | 14848193 |
| MDL Number | MFCD00892750 |
| SMILES | FC(F)(F)c1ccc(N2CCNCC2)nc1Cl |
| InChI | InChI=1S/C10H11ClF3N3/c11-9-7(10(12,13)14)1-2-8(16-9)17-5-3-15-4-6-17/h1-2,15H,3-6H2 |
| InChI Key | QZYYPQAYSFBKPW-UHFFFAOYSA-N |
| Use of | Properties Name 1-[6-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazine Synonym More Synonyms Org 12962 Biological Activity Related Catalog Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor 5-HT2A Receptor:6.38 (pEC50) 5-HT2B Receptor:6.28 (pEC50) References [3]. Faassen F, et al. Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.Int J Pharm. 2003 Sep 16;263(1-2):113-22. Chemical & Physical Properties Exact Mass 265.05900 PSA 28.16000 LogP 2.55720 Index of Refraction 1.541 InChIKey QZYYPQAYSFBKPW-UHFFFAOYSA-N Safety Information HS Code 2933990090 Precursor & DownStream Precursor 2 CAS#:110-85-0 Piperazine CAS#:55304-75-1 2,6-Dichloro-3-... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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