| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1350514-68-9 |
| Catalog No. | 2A-3186647 |
| Chinese Name | 格拉瑞韦 |
| Synonyms | UNII-8YE81R1X1J; MK-5172; CS-1374; grazoprevir; MK5172 |
| Molecular Formula | C38H50O9N6S1 |
| Molecular Weight | 766.92 |
| Density | 1.4±0.1 g/cm3 |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Grazoprevir (MK-5172) is a selective hepatitis C virus NS3/4a protease inhibitor with Ki of 0.01 nM, 0.01 nM, 0.08 nM, 0.15 nM and 0.90 nM for gt1b, gt1a, gt2a, gt2b and gt3a respectively. |
| PubChem ID | 85332785 |
| MDL Number | MFCD25976700 |
| SMILES | C=CC1CC1(NC(=O)C1CC2CN1C(=O)C(C(C)(C)C)NC(=O)OC1CC1CCCCCc1nc3ccc(OC)cc3nc1O2)C(=O)NS(=O)(=O)C1CC1 |
| InChI | InChI=1S/C38H50N6O9S/c1-6-22-19-38(22,35(47)43-54(49,50)25-13-14-25)42-32(45)29-18-24-20-44(29)34(46)31(37(2,3)4)41-36(48)53-30-16-21(30)10-8-7-9-11-27-33(52-24)40-28-17-23(51-5)12-15-26(28)39-27/h6,12,15,17,21-22,24-25,29-31H,1,7-11,13-14,16,18-20H2,2-5H3,(H,41,48)(H,42,45)(H,43,47)/t21-,22-,24-,29+,30-,31-,38-/m1/s1 |
| InChI Key | OBMNJSNZOWALQB-NCQNOWPTSA-N |
| Transport Info | Product name: MK-5172 |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| PF-00299804 | 1042385-75-0 | 2A-3186637 |
| 1847461-43-1 | 1847461-43-1 | 2A-3186638 |
| Methyl 2,3,4-trifluoro-5-nitrobenzoate | 918321-24-1 | 2A-3186639 |
| 788Succinic acid | 2389149-74-8 | 2A-3186640 |
| arsenic acid, sodium salt | 7631-89-2 | 2A-1186644 |
| MK 5172 hydrate | 1350462-55-3 | 2A-3186648 |
| LEE011 (hydrochloride) | 1211443-80-9 | 2A-3186651 |
| TRIMETHYLHYDRAZINE | 1741-01-1 | 2A-3186654 |
| 2,4,6-TRIFLUOROBENZOYL CHLORIDE | 79538-29-7 | 2A-3186656 |
| 2-Propenoic acid, 3-iodo-, 1-methylethyl ester, (2Z)- | 1333154-26-9 | 2A-3186657 |
| Browse all Specialty Chemicals products » | ||
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