| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1042385-75-0 |
| Catalog No. | 2A-3186637 |
| Chinese Name | (2E)-N-[4-[(3-氯-4-氟苯基)氨基]-7-甲氧基-6-喹唑啉基]-4-(1-哌啶基)-2-丁烯酰胺水合物 |
| Synonyms | Dacomitinib [USAN:INN]; UNII-5092U85G58; Dacomitinib; dacomitinib hydrate; Dacomitinib hydrate (JAN); Dacomitinib monohydrate; PF-00299804 |
| Molecular Formula | C24H27O3N5Cl1F1 |
| Molecular Weight | 487.96 |
| Storage Condition | -20°C, dry, sealed |
| Application | Dacomitinib (PF-00299804) hydrate is an orally active, irreversible pan-ErbB inhibitor. Dacomitinib hydrate can be used in the research of cancers such as metastatic non-small cell lung cancer [1]. |
| MDL Number | MFCD28137714 |
| SMILES | COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCN1CCCCC1.O |
| InChI | InChI=1S/C24H25ClFN5O2/c1-33-22-14-20-17(24(28-15-27-20)29-16-7-8-19(26)18(25)12-16)13-21(22)30-23(32)6-5-11-31-9-3-2-4-10-31/h5-8,12-15H,2-4,9-11H2,1H3,(H,30,32)(H,27,28,29)/b6-5+ |
| InChI Key | BSPLGGCPNTZPIH-IPZCTEOASA-N |
| Transport Info | Product name: (2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidyl)-2-butenamide hydrate |
| Related Products in Specialty Chemicals | ||
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| N-(2-HYDROXYETHYL)HEXAMETHYLENEIMINE | 20603-00-3 | 2A-3186636 |
| 1847461-43-1 | 1847461-43-1 | 2A-3186638 |
| Methyl 2,3,4-trifluoro-5-nitrobenzoate | 918321-24-1 | 2A-3186639 |
| 788Succinic acid | 2389149-74-8 | 2A-3186640 |
| arsenic acid, sodium salt | 7631-89-2 | 2A-1186644 |
| MK5172 | 1350514-68-9 | 2A-3186647 |
| Browse all Specialty Chemicals products » | ||
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