CAS Number9050-04-8
SynonymsN-(2-Chloro-7-methoxy-9-acridinyl)-N,N-diethyl-1,4-pentanediamine; Carboxymethyloxysuccinate; 2-Oxa-1,3,4-butantricarbonsaeure; 2-(carboxymethyloxy)butanedioic acid; carboxymethyl ether,calcium salt; CARBOXYMETHYLOXYSUCCINIC ACID; (Carboxymethoxy) succinic acid; carboxymethyl cellulose-calcium
Molecular FormulaC23H30ClN3O
Molecular Weight399.957
Density1.2±0.1 g/cm3
Boiling Point557.1±50.0 °C at 760 mmHg
AppearanceWhite to light yellow solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 9050-04-8 |
| Catalog No. | 2A-1186391 |
| Chinese Name | 羧甲基纤维素钙 |
| Synonyms | N-(2-Chloro-7-methoxy-9-acridinyl)-N,N-diethyl-1,4-pentanediamine; Carboxymethyloxysuccinate; 2-Oxa-1,3,4-butantricarbonsaeure; 2-(carboxymethyloxy)butanedioic acid; carboxymethyl ether,calcium salt; CARBOXYMETHYLOXYSUCCINIC ACID; (Carboxymethoxy) succinic acid; carboxymethyl cellulose-calcium |
| Molecular Formula | C23H30ClN3O |
| Molecular Weight | 399.957 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 557.1±50.0 °C at 760 mmHg |
| Appearance | White to light yellow solid |
| Storage Condition | room temperature, sealed |
| Application | Calcium carboxymethylcellulose can be used as an excipient. Pharmaceutical excipients, or pharmaceutical excipients, refer to other chemical substances used in the pharmaceutical process in addition t |
| HTC | 3912310000 |
| MDL Number | MFCD00197782 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Use of | Calcium carboxymethyl cellulose can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1]. Properties Name N4-(2-Chloro-7-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine Synonym More Synonyms Biological Activity Description Calcium carboxymethyl cellulose can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99. Chemical & Physical Properties Exact Mass 399.207733 PSA 40.62000 Index of Refraction 1.623 Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Cellulose, carboxymethyl ether, calcium salt CAS REGISTRY NUMBER : LAST UPDATED : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - muscle contraction or spasticity Kidney, Ureter, Bladder - changes in bladder weight REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993 TYPE OF TEST : LC - Lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - muscle contraction or spasticity Kidney, Ureter, Bladder - changes in bladder weight REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993 TYPE OF TEST : LC - Lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993 TYPE OF TEST : LC - Lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993 TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : TOXIC EFFECTS : Blood - changes in erythrocyte (RBC) count REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2450 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 738 (estimated) No. of Female Employees: 369 (estimated) Safety Information Signal Word Danger Hazard Statements H317-H334 Precautionary Statements P261-P280-P284-P304 + P340-P342 + P311 RIDADR NONH for all modes of transport HS Code 3912310000 |
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