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H-LEU-AMC HCL

Name: H-LEU-AMC HCL
Brand: 2A Biotech
SKU: 2A-1184636

CAS Number62480-44-8

SynonymsMFCD00043262; 2-amino-4-methyl-N-(4-methyl-2-oxochromen-7-yl)pentanamide,hydrochloride; H-Leu-AMC.HCL

Molecular FormulaC16H21ClN2O3

Molecular Weight324.80

Boiling Point503ºC at 760 mmHg

Melting Point248ºC

AppearanceWhite to almost white powder

MSDSChinese English

Cat. No.: 2A-1184636 Purity:

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Quality Control of [ 62480-44-8 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	62480-44-8
Catalog No.	2A-1184636
Chinese Name	L-亮氨酸-7-氨基-4-甲基香豆素盐酸盐
Synonyms	MFCD00043262; 2-amino-4-methyl-N-(4-methyl-2-oxochromen-7-yl)pentanamide,hydrochloride; H-Leu-AMC.HCL
Molecular Formula	C16H21ClN2O3
Molecular Weight	324.80
Boiling Point	503ºC at 760 mmHg
Melting Point	248ºC
Appearance	White to almost white powder
Storage Condition	Store in an airtight container in a cool, dry plac
Application	L-Leucine-7-amino-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorescent peptide-based substrate of LAP3 (leucine aminopeptidase). L-leucine-7-amino-4-methylcoumarin hydrochloride can b
HTC	2932209090
PubChem ID	24896303
MDL Number	MFCD00043262
SMILES	Cc1cc(=O)oc2cc(NC(=O)C(N)CC(C)C)ccc12.Cl
InChI	InChI=1S/C16H20N2O3/c1-9(2)6-13(17)16(20)18-11-4-5-12-10(3)7-15(19)21-14(12)8-11/h4-5,7-9,13H,6,17H2,1-3H3,(H,18,20)/p+1/t13-/m0/s1
InChI Key	VCRXITKKWBOQRZ-ZOWNYOTGSA-N
NACRES Code	NA.32
UNSPSC	12352204
Bioactivity	L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro In leucine aminopeptidases inhibition assays in KB 3.1 cells. Compounds 3 and 5 are observed to weakly inhibit the biofilm formation by S. aureus and constrain inhibitory activity of ʟ-Leu-AMC hydrolysis in KB 3.1 cells[1]. The amount of hydrolyzed 7-amino-4-methylcoumarin (AMC) is determined in a fluorescence spectrophotometer (excitation/emission: 365/440 nm)[1]. References [1]. Tian Cheng, et al. Skeletocutins M-Q: biologically active compounds from the fruiting bodies of the basidiomycete Skeletocutis sp. collected in Africa. Beilstein J Org Chem Chemical & Physical Properties Boiling Point 503ºC at 760 mmHg Melting Point 248ºC Molecular Formula C16H21ClN2O3 Molecular Weight 324.80300 Flash Point 258ºC Exact Mass 324.12400 PSA 85.33000 LogP 3.98860 InChIKey VCRXITKKWBOQRZ-ZOWNYOTGSA-N SMILES Cc1cc(=O)oc2cc(NC(=O)C(N)CC(C)C)ccc12.Cl Storage condition -20°C
Use of	L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro[1]. Properties Name L-Leucine-(4-methyl-7-coumarinylamide) hydrochloride Synonym More Synonyms L-LEUCINE-7-AMINO-4-METHYLCOUMARIN HCL Biological Activity Description L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Tian Cheng, et al. Skeletocutins M-Q: biologically active compounds from the fruiting bodies of the basidiomycete Skeletocutis sp. collected in Africa. Beilstein J Org Chem Chemical & Physical Properties Exact Mass 324.12400 PSA 85.33000 LogP 3.98860 InChIKey VCRXITKKWBOQRZ-ZOWNYOTGSA-N
Tax Rebate	13.0%
Supervision	None. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport Info	Product name: Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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H-LEU-AMC HCL

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