CAS Number106-25-2
SynonymsNerol; NEROL BJ; (Z)-3,7-Dimethylocta-2,6-dien-1-ol; NEROLEX; cis-2,6-Dimethyl-2,6-octadien-8-ol; FEMA 2770; (2Z)-3,7-Dimethyl-2,6-octadien-1-ol; Vernol; EINECS 203-378-7; NEROL 70; NERYL ALCOHOL; cis-3,7-Dimethyl-2,6-octadien-1-ol; MFCD00063204; Neraniol; cis-3,7-Dimethyl-2,6-octadien-1-ol,Nerol; (Z)-Nerol; (2Z)-3,7-Dimethylocta-2,6-dien-1-ol
Molecular Formula(CH3)2C=CHCH2CH2C(CH3)=CHCH2OH
Molecular Weight154.25
Purity97%
Density0.9±0.1 g/cm3
Boiling Point103-105 °C/9 mmHg (lit.)
Melting Point< -10ºC
Appearanceliquid
EINECS203-378-7
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 106-25-2 |
| Catalog No. | 2A-9018480 |
| Chinese Name | 橙花醇 |
| Synonyms | Nerol; NEROL BJ; (Z)-3,7-Dimethylocta-2,6-dien-1-ol; NEROLEX; cis-2,6-Dimethyl-2,6-octadien-8-ol; FEMA 2770; (2Z)-3,7-Dimethyl-2,6-octadien-1-ol; Vernol; EINECS 203-378-7; NEROL 70; NERYL ALCOHOL; cis-3,7-Dimethyl-2,6-octadien-1-ol; MFCD00063204; Neraniol; cis-3,7-Dimethyl-2,6-octadien-1-ol,Nerol; (Z)-Nerol; (2Z)-3,7-Dimethylocta-2,6-dien-1-ol |
| Molecular Formula | (CH3)2C=CHCH2CH2C(CH3)=CHCH2OH |
| Molecular Weight | 154.25 |
| Purity | 97 |
| Density | 0.9±0.1 g/cm3 |
| Boiling Point | 103-105 °C/9 mmHg (lit.) |
| Melting Point | < -10ºC |
| Appearance | liquid |
| Storage Condition | 1. The preparation method of nerolidol mainly adop |
| Application | Nerol, a component of neroli oil, triggers mitochondrial dysfunction and induces apoptosis by enhancing Ca2+ and ROS. Has antifungal activity. |
| EINECS | 203-378-7 |
| HTC | 2907299090 |
| PubChem ID | 24856300 |
| MDL Number | MFCD00063204 |
| SMILES | C\C(C)=C\CC\C(C)=C/CO |
| InChI | 1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7- |
| InChI Key | GLZPCOQZEFWAFX-YFHOEESVSA-N |
| Beilstein/REAXYS | 1722455 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| MSDS | msds/18480_1_106_25_2.pdf |
| Bioactivity | Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca2+ and ROS. Antifungal activity[1][2]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal In Vitro Nerol induces apoptosis associated with the generation of ROS and Ca2+ overload in saprotrophic fungus Aspergillus flavus[1]. The antifungal activity of Nerol (NEL) against Candida albicans, a pathogenic fungus, has a minimum inhibitory concentration (MIC) of 4.4μM that causes noteworthy candidacidal activity through an apoptosis-like mechanism[2]. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS in Candida albicans[2]. References [1]. Tian J, et al. Nerol-induced apoptosis associated with the generation of ROS and Ca2+ overload in saprotrophic fungus Aspergillus flavus. Appl Microbiol Biotechnol. 2018 Aug;102(15):6659-6672. [2]. Tian J, et al. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS in Candida albicans. Int J Biochem Cell Biol. 2017 Apr;85:114-122. Chemical & Physical Properties Density 0.9±0.1 g/cm3 Boiling Point 229.5±0.0 °C at 760 mmHg Melting Point < -10ºC Molecular Formula C10H18O Molecular Weight 154.249 Flash Point 76.7±0.0 °C Exact Mass 154.135757 PSA 20.23000 LogP 3.28 Vapour Pressure 0.0±1.0 mmHg at 25°C Index of Refraction 1.471 InChIKey GLZPCOQZEFWAFX-YFHOEESVSA-N SMILES CC(C)=CCCC(C)=CCO |
| Use of | Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca2+ and ROS. Antifungal activity[1][2]. Properties Articles39 Name nerol Synonym More Synonyms cis-3,7-Dimethyl-2,6-octadien-1-ol Biological Activity Description Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca2+ and ROS. Antifungal activity[1][2]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal In Vitro Nerol induces apoptosis associated with the generation of ROS and Ca2+ overload in saprotrophic fungus Aspergillus flavus[1]. The antifungal activity of Nerol (NEL) against Candida albicans, a pathogenic fungus, has a minimum inhibitory concentration (MIC) of 4.4μM that causes noteworthy candidacidal activity through an apoptosis-like mechanism[2]. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS in Candida albicans[2]. References [1]. Tian J, et al. Nerol-induced apoptosis associated with the generation of ROS and Ca2+ overload in saprotrophic fungus Aspergillus flavus. Appl Microbiol Biotechnol. 2018 Aug;102(15):6659-6672. [2]. Tian J, et al. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS in Candida albicans. Int J Biochem Cell Biol. 2017 Apr;85:114-122. Chemical & Physical Properties Molecular Formula C10H18O Exact Mass 154.135757 PSA 20.23000 Index of Refraction 1.471 InChIKey GLZPCOQZEFWAFX-YFHOEESVSA-N SMILES CC(C)=CCCC(C)=CCO |
| Tax Rebate | 9.0% |
| Supervision | None. Minimum tariff: 5.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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