
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1621862-70-1 |
| Catalog No. | 2A-1182965 |
| Chinese Name | CPI-1205 |
| Synonyms | Target; References |
| Molecular Formula | C27H33F3N4O3 |
| Molecular Weight | 518.571 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 692.5±55.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | CPI-1205 is a potent and selective inhibitor of the histone methyltransferase EZH2 (IC50 is 2 nM in biochemical assays. EC50 is 32 nM in cellular assays). |
| PubChem ID | 209268260 |
| SMILES | COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n(C(C)C2CCN(CC(F)(F)F)CC2)c2ccccc12 |
| InChI | InChI=1S/C27H33F3N4O3/c1-16-13-23(37-4)21(25(35)32-16)14-31-26(36)24-18(3)34(22-8-6-5-7-20(22)24)17(2)19-9-11-33(12-10-19)15-27(28,29)30/h5-8,13,17,19H,9-12,14-15H2,1-4H3,(H,31,36)(H,32,35)/t17-/m1/s1 |
| InChI Key | HPODOLXTMDHLLC-QGZVFWFLSA-N |
| Transport Info | Product name: CPI-1205 |
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