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BMS-911543 structure, CAS 1271022-90-2

BMS-911543

CAS Number1271022-90-2

SynonymsBMS-911543

Molecular FormulaC23H28N8O

Molecular Weight432.53

Purity

Density1.5±0.1 g/cm3

Boiling Point709.5±70.0 °C at 760 mmHg

Melting Point

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-0182958 Purity:
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Quality Control of [ 1271022-90-2 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number1271022-90-2
Catalog No.2A-0182958
Chinese NameBMS-911543
SynonymsBMS-911543
Molecular FormulaC23H28N8O
Molecular Weight432.53
Density1.5±0.1 g/cm3
Boiling Point709.5±70.0 °C at 760 mmHg
Appearancepowder
Storage Condition-20℃
ApplicationBMS-911543 is a selective JAK2 inhibitor with an IC50 value of 1.1 nM. It is relatively weakly selective for JAK1, JAK3 and TYK2, with IC50 values ​​of 75, 360 and 66 nM respectively.
PubChem ID113916835
MDL NumberC23H28N8O
InChIInChI=1S/C23H28N8O/c1-5-30-17(23(32)31(14-6-7-14)15-8-9-15)11-16-20-19(24-12-28(20)3)21(26-22(16)30)25-18-10-13(2)29(4)27-18/h10-12,14-15H,5-9H2,1-4H3,(H,25,26,27)
InChI KeyJCINBYQJBYJGDM-UHFFFAOYSA-N
Transport InfoProduct name: BMS 911543
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