CAS Number104-29-0
SynonymsGecophen; Adermykon; Demykon; EINECS 203-192-6; 3-(4-Chlorophenoxy)-1,2-propanediol; 3-(4-chlorophenoxy)propane-1,2-diol; Chlorphenesinum; 3-(p-Chlorophenoxy)propane-1,2-diol; Mycil; p-chlorophenyl a-glyceryl ether; Chlorphenesine; Clorfenesina; MFCD00021990; Chlorphenesin; Chlorophenesin
Molecular FormulaC9H11ClO3
Molecular Weight202.63
Purity≥98.0 (GC)%
Density1.3±0.1 g/cm3
Boiling Point369.5±27.0 °C at 760 mmHg
Melting Point77-79°C
AppearanceWhite to off-white crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 104-29-0 |
| Catalog No. | 2A-9018383 |
| Chinese Name | 氯苯甘醚 |
| Synonyms | Gecophen; Adermykon; Demykon; EINECS 203-192-6; 3-(4-Chlorophenoxy)-1,2-propanediol; 3-(4-chlorophenoxy)propane-1,2-diol; Chlorphenesinum; 3-(p-Chlorophenoxy)propane-1,2-diol; Mycil; p-chlorophenyl a-glyceryl ether; Chlorphenesine; Clorfenesina; MFCD00021990; Chlorphenesin; Chlorophenesin |
| Molecular Formula | C9H11ClO3 |
| Molecular Weight | 202.63 |
| Purity | ≥98.0 (GC) |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 369.5±27.0 °C at 760 mmHg |
| Melting Point | 77-79°C |
| Appearance | White to off-white crystalline powder |
| Storage Condition | Store in a cool, ventilated warehouse. Keep away f |
| Application | Chlorphenesin is a reversible antigen-related immunosuppressant. Chlorphenesin is an antibacterial and antifungal agent used in many eye care cosmetics. |
| HTC | 2909499000 |
| MDL Number | MFCD00021990 |
| SMILES | Clc1ccc(cc1)OCC(O)CO |
| InChI | InChI=1S/C9H11ClO3/c10-7-1-3-9(4-2-7)13-6-8(12)5-11/h1-4,8,11-12H,5-6H2 |
| InChI Key | MXOAEAUPQDYUQM-UHFFFAOYSA-N |
| NACRES Code | NA.21 |
| UNSPSC | 41116107 |
| MSDS | msds/18383_1_104_29_0.pdf |
| Bioactivity | Chlorphenesin is a reversible antigen-associated immunosuppressant. Chlorphenesin is an antibacterial and antifungal agent used in numerous eye care cosmetics[1]. Related Catalog Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial In Vitro Chlorphenesin (0.01, 0.1, 0.3%; 30-min exposure) significantly reduces the activity of the Akt pathway in a dose-dependent manner in human meibomian gland epithelial cells (HMGECs)[2]. Chlorphenesin (0.1, 0.3%; 24 hours) induces immortalized HMGECs (IHMGECs) rounding, atrophy, poor adherence, detachme and significantly reduces the number of IHMGECs[2]. References [1]. H Y Whang, et al. Chlorphenesin: an antigen-associated immunosuppressant. Infect Immun. 1970 Jul;2(1):60-4. [2]. Jingyi Wang, et al. Toxicity of the cosmetic preservatives parabens, phenoxyethanol and chlorphenesin on human meibomian gland epithelial cells. Exp Eye Res. 2020 Jul;196:108057. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 369.5±27.0 °C at 760 mmHg Melting Point 77-79°C Molecular Formula C9H11ClO3 Molecular Weight 202.635 Flash Point 177.2±23.7 °C Exact Mass 202.039673 PSA 49.69000 LogP 1.43 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.565 InChIKey MXOAEAUPQDYUQM-UHFFFAOYSA-N SMILES OCC(O)COc1ccc(Cl)cc1 |
| Use of | Chlorphenesin is a reversible antigen-associated immunosuppressant. Chlorphenesin is an antibacterial and antifungal agent used in numerous eye care cosmetics[1]. Properties Name chlorphenesin Synonym More Synonyms Chlorphenesin Biological Activity Description Chlorphenesin is a reversible antigen-associated immunosuppressant. Chlorphenesin is an antibacterial and antifungal agent used in numerous eye care cosmetics[1]. Related Catalog Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial In Vitro Chlorphenesin (0.01, 0.1, 0.3%; 30-min exposure) significantly reduces the activity of the Akt pathway in a dose-dependent manner in human meibomian gland epithelial cells (HMGECs)[2]. Chlorphenesin (0.1, 0.3%; 24 hours) induces immortalized HMGECs (IHMGECs) rounding, atrophy, poor adherence, detachme and significantly reduces the number of IHMGECs[2]. References [1]. H Y Whang, et al. Chlorphenesin: an antigen-associated immunosuppressant. Infect Immun. 1970 Jul;2(1):60-4. [2]. Jingyi Wang, et al. Toxicity of the cosmetic preservatives parabens, phenoxyethanol and chlorphenesin on human meibomian gland epithelial cells. Exp Eye Res. 2020 Jul;196:108057. Chemical & Physical Properties Exact Mass 202.039673 PSA 49.69000 Index of Refraction 1.565 InChIKey MXOAEAUPQDYUQM-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 4-Chloro-N-methylbenzylamine | 104-11-0 | 2A-9018373 |
| 4-Butylaniline | 104-13-2 | 2A-9018375 |
| Anisyl acetate | 104-21-2 | 2A-9018380 |
| 4'-Aminoazobenzene-4-sulphonic acid | 104-23-4 | 2A-9018381 |
| 1-(4-Methoxyphenyl)-1-penten-3-one | 104-27-8 | 2A-9018382 |
| Benzonatate | 104-31-4 | 2A-9018384 |
| Hydroquinone bis(2-hydroxyethyl)ether | 104-38-1 | 2A-9018386 |
| 4-Dodecylaniline | 104-42-7 | 2A-9018387 |
| cis-Anethol | 104-46-1 | 2A-9018388 |
| 1-Chloro-3-phenylpropane | 104-52-9 | 2A-9018393 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS