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IDRA 21

Name: IDRA 21
Brand: 2A Biotech
SKU: 2A-2178099

CAS Number22503-72-6

Synonyms7-chloro-3,4-dihydro-3-methyl-2h-1,2,4-benzothiadiazine 1,1-dioxide; 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-S,S-dioxide; MFCD00270874; IDRA 21; 2H-1,2,4-Benzothiadiazine, 7-chloro-3,4-dihydro-3-methyl-, 1,1-dioxide; Gadolinium chloride; 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide; 7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE

Molecular FormulaC8H9ClN2O2S

Molecular Weight232.69

Purity≥98%

Density1.4±0.1 g/cm3

Boiling Point405.1±55.0 °C at 760 mmHg

MSDSChinese English

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Cat. No.: 2A-2178099 Purity: ≥98%

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Quality Control of [ 22503-72-6 ] Purity: ≥98% SDS Specification MoL

Chemical & Physical Properties
CAS Number	22503-72-6
Catalog No.	2A-2178099
Chinese Name	7-氯-3-甲基-3,4-二氢-2H-1,2,4-苯并噻二嗪-1,1-二氧化物
Synonyms	7-chloro-3,4-dihydro-3-methyl-2h-1,2,4-benzothiadiazine 1,1-dioxide; 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-S,S-dioxide; MFCD00270874; IDRA 21; 2H-1,2,4-Benzothiadiazine, 7-chloro-3,4-dihydro-3-methyl-, 1,1-dioxide; Gadolinium chloride; 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide; 7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE
Molecular Formula	C8H9ClN2O2S
Molecular Weight	232.69
Purity	≥98
Density	1.4±0.1 g/cm3
Boiling Point	405.1±55.0 °C at 760 mmHg
Storage Condition	Sealed in a cool, dry environment at 0-6 ºC
Application	IDRA 21 is a positive orally active modulator of the AMPA receptor. IDRA 21 promotes excitatory neurotransmission through GluR1/2 receptors. IDRA 21 has the potential to study cognitive/memory disorde
HTC	2933990090
PubChem ID	24896078
MDL Number	MFCD00270874
SMILES	CC1Nc2ccc(Cl)cc2S(=O)(=O)N1
InChI	1S/C8H9ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-5,10-11H,1H3
InChI Key	VZRNTCHTJRLTMU-UHFFFAOYSA-N
NACRES Code	NA.77
UNSPSC	12352200
Hazard Symbols	transportation
MSDS	msds/178730_1_22503_72_6.pdf
Bioactivity	IDRA 21 is a positive and orally active modulator of the AMPA receptor. IDRA 21 facilitates excitatory neurotransmission via GluR1/2 receptors. IDRA 21 has the potential for the research of cognitive/memory disorders, including those associated with aging[1]. Related Catalog Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR References [1]. Buccafusco JJ, et al. The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys. Neuropharmacology. 2004 Jan;46(1):10-22. doi: 10.1016/j.neuropharm.2003.07.002. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 405.1±55.0 °C at 760 mmHg Molecular Formula C8H9ClN2O2S Molecular Weight 232.69 Flash Point 198.8±31.5 °C Exact Mass 232.007324 PSA 66.58000 LogP 0.77 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.572 InChIKey VZRNTCHTJRLTMU-UHFFFAOYSA-N SMILES CC1Nc2ccc(Cl)cc2S(=O)(=O)N1
Use of	Properties Articles19 Name IDRA 21,7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazineS,S-dioxide Synonym More Synonyms Biological Activity Related Catalog Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR References Chemical & Physical Properties Exact Mass 232.007324 PSA 66.58000 Index of Refraction 1.572 InChIKey VZRNTCHTJRLTMU-UHFFFAOYSA-N
Tax Rebate	13.0%
Supervision	None. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport Info	Product name: Purity: 98.0%
MSDS Transport Info	Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available

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IDRA 21

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