CAS Number92-48-8
Synonyms6-Methyl-2H-1-benzopyran-2-one; 6-Methyl-2H-chromen-2-one; 6-methylchromen-2-one; 6-Methylcoumarin; T66 BOVJ H1; EINECS 202-158-8; MFCD00006875
Molecular FormulaC10H8O2
Molecular Weight160.17
Purity≥99%
Density1.2±0.1 g/cm3
Boiling Point303 °C/725 mmHg (lit.)
Melting Point73-76 °C (lit.)
AppearanceWhite crystalline powder
EINECS202-158-8
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 92-48-8 |
| Catalog No. | 2A-9017749 |
| Chinese Name | 6-甲基香豆素 |
| Synonyms | 6-Methyl-2H-1-benzopyran-2-one; 6-Methyl-2H-chromen-2-one; 6-methylchromen-2-one; 6-Methylcoumarin; T66 BOVJ H1; EINECS 202-158-8; MFCD00006875 |
| Molecular Formula | C10H8O2 |
| Molecular Weight | 160.17 |
| Purity | ≥99 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 303 °C/725 mmHg (lit.) |
| Melting Point | 73-76 °C (lit.) |
| Appearance | White crystalline powder |
| Storage Condition | This product should be sealed and stored in a cool |
| Application | 6-Methylcumarin is a synthetic fragrance widely used in cosmetics. |
| EINECS | 202-158-8 |
| HTC | 2932209090 |
| PubChem ID | 24896858 |
| MDL Number | MFCD00006875 |
| SMILES | Cc1ccc2OC(=O)C=Cc2c1 |
| InChI | 1S/C10H8O2/c1-7-2-4-9-8(6-7)3-5-10(11)12-9/h2-6H,1H3 |
| InChI Key | FXFYOPQLGGEACP-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/17749_1_92_48_8.pdf |
| Bioactivity | 6-Methylcoumarin is a synthetic fragrance widely used in cosmetics. Related Catalog Signaling Pathways >> Others >> Others Natural Products >> Phenylpropanoids Research Areas >> Others In Vitro 6-Methylcoumarin is reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models. HaCaT cells are treated with 6-Methylcoumarin (1-105 nM) and/or UVA (5 J cm-2), and γ-H2AX is detected by immunofluorescence staining and western blotting 4hours after the treatments. 6-Methylcoumarin clearly produces γ-H2AX-positive cells under UVA irradiation from a concentration of 100 nM[1]. References [1]. Toyooka T, et al. Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity. J Invest Dermatol. 2011 Jun;131(6):1313-21. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 304.6±21.0 °C at 760 mmHg Melting Point 73-76 °C(lit.) Molecular Formula C10H8O2 Molecular Weight 160.169 Flash Point 124.3±19.5 °C Exact Mass 160.052429 PSA 30.21000 LogP 1.85 Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.583 InChIKey FXFYOPQLGGEACP-UHFFFAOYSA-N SMILES Cc1ccc2oc(=O)ccc2c1 |
| Use of | 6-Methylcoumarin is a synthetic fragrance widely used in cosmetics. Properties Articles29 Name 6-methylcoumarin Synonym More Synonyms 6-Methylcoumarin Biological Activity Description 6-Methylcoumarin is a synthetic fragrance widely used in cosmetics. Related Catalog Signaling Pathways >> Others >> Others Natural Products >> Phenylpropanoids Research Areas >> Others In Vitro 6-Methylcoumarin is reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models. HaCaT cells are treated with 6-Methylcoumarin (1-105 nM) and/or UVA (5 J cm-2), and γ-H2AX is detected by immunofluorescence staining and western blotting 4hours after the treatments. 6-Methylcoumarin clearly produces γ-H2AX-positive cells under UVA irradiation from a concentration of 100 nM[1]. References [1]. Toyooka T, et al. Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity. J Invest Dermatol. 2011 Jun;131(6):1313-21. Chemical & Physical Properties Molecular Formula C10H8O2 Exact Mass 160.052429 PSA 30.21000 Index of Refraction 1.583 InChIKey FXFYOPQLGGEACP-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip. |
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