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SPIPERONE structure, CAS 749-02-0

SPIPERONE

CAS Number749-02-0

Synonyms8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; Spiroperidol; Espiperona; R 5147; Spiperonum; Spiropitan

Molecular FormulaC23H26O2N3F1

Molecular Weight395.48

Purity98.00%

Density

Boiling Point630.6ºC at 760 mmHg

Melting Point190-193.6ºC

Flash Point

Appearance

EINECS

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Cat. No.: 2A-1176587 Purity: 98.00%
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Quality Control of [ 749-02-0 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number749-02-0
Catalog No.2A-1176587
Chinese Name螺哌隆
Synonyms8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; Spiroperidol; Espiperona; R 5147; Spiperonum; Spiropitan
Molecular FormulaC23H26O2N3F1
Molecular Weight395.48
Purity98.00
Boiling Point630.6ºC at 760 mmHg
Melting Point190-193.6ºC
Storage Condition2-8°C
ApplicationSpiperone is a potent dopamine D2, serotonin 5-HT1A and serotonin 5-HT2A antagonist. Spiperone is a widely used pharmacological tool. Spiperone has potential in the study of neurological diseases [1].
MDL NumberMFCD00055099
SMILESFc1ccc(cc1)C(=O)CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4
InChIInChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)
InChI KeyInChIKey=DKGZKTPJOSAWFA-UHFFFAOYSA-N
Hazard Symbolstransportation
MSDSmsds/177114_1_749_02_0.pdf
BioactivitySpiperone is a potent dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist. Spiperone is a widely used pharmacological tool. Spiperone has the potential for the research of neurology diseases[1]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor References [1]. Metwally KA, et al. Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding. J Med Chem. 1998;41(25):5084-5093. Chemical & Physical Properties Boiling Point 630.6ºC at 760 mmHg Melting Point 190-193.6ºC Molecular Formula C23H26FN3O2 Molecular Weight 395.47 Flash Point 335.2ºC Exact Mass 395.20100 PSA 52.65000 LogP 3.54880 Storage condition 2-8°C
Use ofSpiperone is a potent dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist. Spiperone is a widely used pharmacological tool. Spiperone has the potential for the research of neurology diseases[1]. Properties Articles49 Name spiperone Synonym More Synonyms Spiperone Biological Activity Description Spiperone is a potent dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist. Spiperone is a widely used pharmacological tool. Spiperone has the potential for the research of neurology diseases[1]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor References [1]. Metwally KA, et al. Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding. J Med Chem. 1998;41(25):5084-5093. Chemical & Physical Properties Molecular Formula C23H26FN3O2 Exact Mass 395.20100 PSA 52.65000 LogP 3.54880
Transport InfoProduct name: Purity: 95.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip.
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