CAS Number88-58-4
Synonyms2,5-Bis(2-methyl-2-propanyl)-1,4-benzenediol; MFCD00008825; 2,5-TBHQ; EINECS 201-841-8; 2,5-Di-tert-Butyl-1,4-hydroquinone (DBHQ); 2,5-di-tert-butylhydroquinone; 2,5-Di-tert-butylbenzene-1,4-diol; 2,5-DITERT-BUTYLBENZENE-1,4-DIOL; 2,5-Di-tert-butyl-1,4-hydroquinone
Molecular Formula[(CH3)3C]2C6H2-1,4-(OH)2
Molecular Weight222.32
Purity99%
Density1.0±0.1 g/cm3
Boiling Point334.4±37.0 °C at 760 mmHg
Melting Point216-218 °C (lit.)
Appearancesolid
EINECS201-841-8
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 88-58-4 |
| Catalog No. | 2A-9017574 |
| Chinese Name | 2,5-二叔丁基对苯二酚 |
| Synonyms | 2,5-Bis(2-methyl-2-propanyl)-1,4-benzenediol; MFCD00008825; 2,5-TBHQ; EINECS 201-841-8; 2,5-Di-tert-Butyl-1,4-hydroquinone (DBHQ); 2,5-di-tert-butylhydroquinone; 2,5-Di-tert-butylbenzene-1,4-diol; 2,5-DITERT-BUTYLBENZENE-1,4-DIOL; 2,5-Di-tert-butyl-1,4-hydroquinone |
| Molecular Formula | [(CH3)3C]2C6H2-1,4-(OH)2 |
| Molecular Weight | 222.32 |
| Purity | 99 |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 334.4±37.0 °C at 760 mmHg |
| Melting Point | 216-218 °C (lit.) |
| Appearance | solid |
| Water Solubility | Water solubility: insoluble; water solubility: 0.0 |
| Storage Condition | This product should be stored in a sealed, cool, d |
| Application | 2,5-Di-tert-butylhydroquinone (DTBHQ) is an indirect food additive that modulates 5-LO and COX-2 activities with IC50 of 1.8 and 14.1 μM, respectively. |
| EINECS | 201-841-8 |
| HTC | 29072900 |
| PubChem ID | 24847124 |
| MDL Number | MFCD00008825 |
| SMILES | CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C |
| InChI | 1S/C14H22O2/c1-13(2,3)9-7-12(16)10(8-11(9)15)14(4,5)6/h7-8,15-16H,1-6H3 |
| InChI Key | JZODKRWQWUWGCD-UHFFFAOYSA-N |
| Beilstein/REAXYS | 2049542 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/17574_2_88_58_4.pdf |
| Bioactivity | 2,5-Di-tert-butylhydroquinone (DTBHQ), the indirect food additive, regulates the activity of 5-lipoxygenase as well as the activity of COX-2 (IC50=1.8 and 14.1 μM for 5-LO and COX-2, respectively) [1]. Related Catalog Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase Signaling Pathways >> Immunology/Inflammation >> COX Target 5-LO:1.8 μM (IC50) COX-2:14.1 μM (IC50) In Vitro DTBHQ influences arachidonic acid (AA) metabolism in biologically relevant concentrations in vitro[1]. References [1]. Zsofia Kutil, et al. The influence of the quinone antioxidants tert-butylhydroquinone and 2,5-di-tert-butylhydroquinone on the arachidonic acid metabolism in vitro. Food and Agricultural Immunology. Volume 26, 2015-Issue 4. Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 334.4±37.0 °C at 760 mmHg Melting Point 216-218 °C(lit.) Molecular Formula C14H22O2 Molecular Weight 222.323 Flash Point 151.5±21.1 °C Exact Mass 222.161987 PSA 40.46000 LogP 4.02 Vapour Pressure 0.0±0.8 mmHg at 25°C Index of Refraction 1.520 InChIKey JZODKRWQWUWGCD-UHFFFAOYSA-N SMILES CC(C)(C)c1cc(O)c(C(C)(C)C)cc1O Storage condition Store at RT Stability Stable. Incompatible with oxidizing agents. |
| Use of | 2,5-Di-tert-butylhydroquinone (DTBHQ), the indirect food additive, regulates the activity of 5-lipoxygenase as well as the activity of COX-2 (IC50=1.8 and 14.1 μM for 5-LO and COX-2, respectively) [1]. Properties Articles30 Name 2,5-di-tert-butylbenzene-1,4-diol Synonym More Synonyms 2,5-Di-tert-butylhydroquinone Biological Activity Description 2,5-Di-tert-butylhydroquinone (DTBHQ), the indirect food additive, regulates the activity of 5-lipoxygenase as well as the activity of COX-2 (IC50=1.8 and 14.1 μM for 5-LO and COX-2, respectively) [1]. Related Catalog Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase Signaling Pathways >> Immunology/Inflammation >> COX 5-LO:1.8 μM (IC50) COX-2:14.1 μM (IC50) In Vitro DTBHQ influences arachidonic acid (AA) metabolism in biologically relevant concentrations in vitro[1]. References [1]. Zsofia Kutil, et al. The influence of the quinone antioxidants tert-butylhydroquinone and 2,5-di-tert-butylhydroquinone on the arachidonic acid metabolism in vitro. Food and Agricultural Immunology. Volume 26, 2015-Issue 4. Chemical & Physical Properties Molecular Formula C14H22O2 Exact Mass 222.161987 PSA 40.46000 Index of Refraction 1.520 InChIKey JZODKRWQWUWGCD-UHFFFAOYSA-N Storage condition Store at RT Stability Stable. Incompatible with oxidizing agents. |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Imported food hygiene supervision and inspection S. Export food hygiene supervision and inspection M. Imported commodity inspection N. Exported commodity inspection |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 2-tert-Butylcyclohexyl acetate | 88-41-5 | 2A-9017568 |
| 2,5-Diaminobenzenesulfonic acid | 88-45-9 | 2A-9017570 |
| 4-Amino-2,5-dichlorobenzenesulfonic acid | 88-50-6 | 2A-9017571 |
| 2-Amino-4-chloro-5-methylbenzenesulfonic acid | 88-51-7 | 2A-9017572 |
| 2-Amino-5-chloro-4-methylbenzenesulfonic acid | 88-53-9 | 2A-9017573 |
| 2-Bromobenzoic acid | 88-65-3 | 2A-9017579 |
| 2-Iodobenzoic acid | 88-67-5 | 2A-9017580 |
| Anthranilamide | 88-68-6 | 2A-9017581 |
| 2-Isopropylphenol | 88-69-7 | 2A-9017582 |
| 4-Chloro-3-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzenesulfonic acid | 88-76-6 | 2A-9017587 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS