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Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride
1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride structure, CAS 1028969-49-4

1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride

CAS Number1028969-49-4

SynonymsUrea,1-(1-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)azetidin-3-yl)-1-methyl; 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole trihydrochloride; MCOPPB trihydrochloride; 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1Hbenzimidazole; 1-(1-(10,11-DIHYDRO-5H-DIBENZO(A,D)CYCLOHEPTEN-5-YL)AZETIDIN-3-YL)-1-M ETHYLUREA; Urea,N-[1-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-3-azetidinyl]-N-methyl

Molecular FormulaC26H40N4

Molecular Weight518.01 (anhydrous basis)

Purity>98 (HPLC)%

Density

Boiling Point

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Flash Point

Appearancepowder

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MSDSChineseEnglish

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Cat. No.: 2A-1175020 Purity: >98 (HPLC)%
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Quality Control of [ 1028969-49-4 ] Purity: >98 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number1028969-49-4
Catalog No.2A-1175020
Chinese Name1-(1-(1-甲基环辛基)哌啶-4-基)-2-(哌啶-3-基)-1H-苯并[d]咪唑三盐酸盐
SynonymsUrea,1-(1-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)azetidin-3-yl)-1-methyl; 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole trihydrochloride; MCOPPB trihydrochloride; 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1Hbenzimidazole; 1-(1-(10,11-DIHYDRO-5H-DIBENZO(A,D)CYCLOHEPTEN-5-YL)AZETIDIN-3-YL)-1-M ETHYLUREA; Urea,N-[1-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-3-azetidinyl]-N-methyl
Molecular FormulaC26H40N4
Molecular Weight518.01 (anhydrous basis)
Purity>98 (HPLC)
Appearancepowder
ApplicationMCOPPB is an orally active Nociceptin/Orphanin FQ-Receptor selective agonist. MCOPPB inhibits signaling through NOP receptors in the mouse brain. MCOPPB is used in anxiety disorder research.
PubChem ID329823741
SMILESO.Cl.Cl.Cl.CC1(CCCCCCC1)N2CCC(CC2)n3c(nc4ccccc34)[C@@H]5CCCNC5
InChI1S/C26H40N4.3ClH.H2O/c1-26(15-7-3-2-4-8-16-26)29-18-13-22(14-19-29)30-24-12-6-5-11-23(24)28-25(30)21-10-9-17-27-20-21;;;;/h5-6,11-12,21-22,27H,2-4,7-10,13-20H2,1H3;3*1H;1H2
InChI KeyUQBVSGBDJOJHIP-UHFFFAOYSA-N
NACRES CodeNA.77
UNSPSC51111800
MSDSmsds/175425_1_1028969_49_4.pdf
BioactivityMCOPPB is an orally active and selective agonist of Nociceptin/Orphanin FQ-Receptor. MCOPPB inhibits signaling through the NOP receptor in the mouse brain. MCOPPB is used in anxiety disorders research[1]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease References [1]. Hirao A, et al. Pharmacological characterization of the newly synthesized nociceptin/orphanin FQ-receptor agonist 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an anxiolytic agent. J Pharmacol Sci. 2008 Mar;106(3):361-8. Chemical & Physical Properties Molecular Formula C26H40N4 Molecular Weight 408.62 Exact Mass 516.255310 PSA 33.09000 LogP 8.31590 InChIKey CYYNMPPFEJPBJD-OAQYLSRUSA-N SMILES CC1(N2CCC(n3c(C4CCCNC4)nc4ccccc43)CC2)CCCCCCC1
Use ofMCOPPB is an orally active and selective agonist of Nociceptin/Orphanin FQ-Receptor. MCOPPB inhibits signaling through the NOP receptor in the mouse brain. MCOPPB is used in anxiety disorders research[1]. Properties Name 1-(1-(1-Methylcyclooctyl)piperidin-4-yl)-2-(piperidin-3-yl)-1H-Benzo[d]imidazole trihydrochloride Synonym More Synonyms MCOPPB trihydrochloride Biological Activity Description MCOPPB is an orally active and selective agonist of Nociceptin/Orphanin FQ-Receptor. MCOPPB inhibits signaling through the NOP receptor in the mouse brain. MCOPPB is used in anxiety disorders research[1]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease References [1]. Hirao A, et al. Pharmacological characterization of the newly synthesized nociceptin/orphanin FQ-receptor agonist 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an anxiolytic agent. J Pharmacol Sci. 2008 Mar;106(3):361-8. Chemical & Physical Properties Molecular Formula C26H40N4 Exact Mass 516.255310 PSA 33.09000 LogP 8.31590 InChIKey CYYNMPPFEJPBJD-OAQYLSRUSA-N
Transport InfoProduct name: MCOPPB trihydrochloride hydrate
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