ARRY-334543

Name: ARRY-334543
Brand: 2A Biotech
SKU: 2A-1175016

CAS Number845272-21-1

SynonymsARRY-543; Varlitinib (USAN/INN); Varlitinib

Molecular FormulaC22H19O2N6Cl1S1

Molecular Weight466.95

Density1.5±0.1 g/cm3

Boiling Point637.1±65.0 °C at 760 mmHg

Appearancepowder

Cat. No.: 2A-1175016 Purity:

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Quality Control of [ 845272-21-1 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	845272-21-1
Catalog No.	2A-1175016
Chinese Name	Varlitinib
Synonyms	ARRY-543; Varlitinib (USAN/INN); Varlitinib
Molecular Formula	C22H19O2N6Cl1S1
Molecular Weight	466.95
Density	1.5±0.1 g/cm3
Boiling Point	637.1±65.0 °C at 760 mmHg
Appearance	powder
Storage Condition	-20℃
Application	Varlitinib (ARRY-334543; ASLAN001) is a potent, reversible small molecule inhibitor of pan-EGFR with IC50 values of 7, 2, and 4 nM for HER1, HER2, and HER4, respectively.
PubChem ID	81082090
MDL Number	MFCD20275099
SMILES	CC1COC(Nc2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)=N1
InChI	InChI=1S/C22H19ClN6O2S/c1-13-10-31-22(27-13)29-14-2-4-18-16(8-14)21(26-12-25-18)28-15-3-5-19(17(23)9-15)30-11-20-24-6-7-32-20/h2-9,12-13H,10-11H2,1H3,(H,27,29)(H,25,26,28)/t13-/m1/s1
InChI Key	UWXSAYUXVSFDBQ-CYBMUJFWSA-N
MSDS	msds/175417_1_845272_21_1.pdf
Transport Info	Product name: Varlitinib

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