CAS Number81-07-2
Synonyms3-keto-2H,3H-1,2-benzisothiazole 1,1-dioxide; Sykose; T56 BSWMVJ; Saccharinose; Saccharol; 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide; Sacarina; UNII-FST467XS7D; Sweeta; Saxin; Saccharin; o-Benzoic acid sulfimide; EINECS 201-321-0; Syncal; Kandiset; Natreen; 1,1-dioxo-benzo[d]isothiazol-3-one; 1,1-dioxo-1,2-benzisothiazol-3-one; 1,2-benzisothiazol-3(2H)-one-1,1-dioxide; 1,2-benzoisothiazol-3(2H)-one 1,1-dioxide; o-benzoic sulfimide; 1,2-benzisothiazol-3-one 1,1-dioxide; Gluside; Glycosin; Garantose; SACCHARINOL; MFCD00005866; 1,2-Benzothiazol-3(2H)-one 1,1-dioxide; Glucid
Molecular FormulaC7H5NO3S
Molecular Weight183.18
Purity≥98%
Density1.7±0.1 g/cm3
Boiling Point438.9±28.0 °C at 760 mmHg
Melting Point226-229 °C (lit.)
AppearanceWhite crystalline solid
EINECS201-321-0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 81-07-2 |
| Catalog No. | 2A-9017329 |
| Chinese Name | 糖精 |
| Synonyms | 3-keto-2H,3H-1,2-benzisothiazole 1,1-dioxide; Sykose; T56 BSWMVJ; Saccharinose; Saccharol; 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide; Sacarina; UNII-FST467XS7D; Sweeta; Saxin; Saccharin; o-Benzoic acid sulfimide; EINECS 201-321-0; Syncal; Kandiset; Natreen; 1,1-dioxo-benzo[d]isothiazol-3-one; 1,1-dioxo-1,2-benzisothiazol-3-one; 1,2-benzisothiazol-3(2H)-one-1,1-dioxide; 1,2-benzoisothiazol-3(2H)-one 1,1-dioxide; o-benzoic sulfimide; 1,2-benzisothiazol-3-one 1,1-dioxide; Gluside; Glycosin; Garantose; SACCHARINOL; MFCD00005866; 1,2-Benzothiazol-3(2H)-one 1,1-dioxide; Glucid |
| Molecular Formula | C7H5NO3S |
| Molecular Weight | 183.18 |
| Purity | ≥98 |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 438.9±28.0 °C at 760 mmHg |
| Melting Point | 226-229 °C (lit.) |
| Appearance | White crystalline solid |
| Water Solubility | 3.3 g/L (20 ºC) |
| Storage Condition | This product should be stored in a sealed, cool, d |
| Application | Saccharin is an orally available, non-caloric artificial sweetener (NAS). Saccharin has bacteriostatic and microbial modulating properties. |
| EINECS | 201-321-0 |
| HTC | 2925110000 |
| PubChem ID | 24846892 |
| MDL Number | MFCD00005866 |
| SMILES | O=C1NS(=O)(=O)c2ccccc12 |
| InChI | 1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) |
| InChI Key | CVHZOJJKTDOEJC-UHFFFAOYSA-N |
| Beilstein/REAXYS | 6888 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/17329_1_81_07_2.pdf |
| Bioactivity | Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties[1]. Related Catalog Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial In Vitro In vitro, saccharin (0.5, 2.5, 5 mM) inhibits bacterial growth in a species-dependent manner[1]. In Vivo In vivo, saccharin (oral; 5 mg/kg; twice a day) intake reduces fecal bacterial load and alters microbiome composition, while the intestinal barrier is not obviously affected in male C57BL/6JRj wild type (wt) mice[1]. References [1]. Sünderhauf A, et al. Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice. Nutrients. 2020 Apr 17;12(4). pii: E1122. Chemical & Physical Properties Density 1.7±0.1 g/cm3 Boiling Point 438.9±28.0 °C at 760 mmHg Melting Point 226-229 °C(lit.) Molecular Formula C7H5NO3S Molecular Weight 183.184 Flash Point 219.3±24.0 °C Exact Mass 182.999008 PSA 71.62000 LogP 0.46 Vapour Pressure 0.0±1.1 mmHg at 25°C Index of Refraction 1.714 Stability Stable. Incompatible with strong oxidizing agents. Water Solubility 3.3 g/L (20 ºC) |
| Use of | Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties[1]. Properties Articles120 Name saccharin Synonym More Synonyms Saccharin Biological Activity Description Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties[1]. Related Catalog Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial References [1]. Sünderhauf A, et al. Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice. Nutrients. 2020 Apr 17;12(4). pii: E1122. Chemical & Physical Properties Molecular Formula C7H5NO3S Exact Mass 182.999008 PSA 71.62000 Index of Refraction 1.714 Stability Stable. Incompatible with strong oxidizing agents. |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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