CAS Number6665-83-4
SynonymsEINECS 229-704-8; 6-Monohydroxyflavone; MFCD00017329; 6-hydroxy-2-phenylchromen-4-one; 6-Hydroxy-2-phenyl-4H-chromen-4-one
Molecular FormulaC15H10O3
Molecular Weight238.238
Density1.3±0.1 g/cm3
Boiling Point450.1±45.0 °C at 760 mmHg
Melting Point234-236 °C(lit.)
Appearancelight yellow crystal
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6665-83-4 |
| Catalog No. | 2A-1172290 |
| Chinese Name | 6-羟基黄酮 |
| Synonyms | EINECS 229-704-8; 6-Monohydroxyflavone; MFCD00017329; 6-hydroxy-2-phenylchromen-4-one; 6-Hydroxy-2-phenyl-4H-chromen-4-one |
| Molecular Formula | C15H10O3 |
| Molecular Weight | 238.238 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 450.1±45.0 °C at 760 mmHg |
| Melting Point | 234-236 °C(lit.) |
| Appearance | light yellow crystal |
| Storage Condition | room temperature, dry |
| Application | 6-Hydroxyflavone is a naturally occurring flavonoid compound that has anti-inflammatory properties. 6-Hydroxyflavone has inhibitory effects on bovine hemoglobin (BHb) glycosylation. 6-Hydroxyflavone c |
| HTC | 2914400090 |
| PubChem ID | 87535 |
| SMILES | O=c1cc(-c2ccccc2)oc2ccc(O)cc12 |
| InChI | InChI=1S/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H |
| InChI Key | GPZYYYGYCRFPBU-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | 6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK signaling pathways to effectively promote osteoblastic differentiation. 6-Hydroxyflavone inhibits the LPS-induced NO production[1] [2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Das S, et al. Characterization of non-covalent binding of 6-hydroxyflavone and 5,7-dihydroxyflavone with bovine hemoglobin: Multi-spectroscopic and molecular docking analyses. J Photochem Photobiol B. 2018 Jan;178:40-52. [2]. Lai CH, et al. Effects of 6-Hydroxyflavone on Osteoblast Differentiation in MC3T3-E1 Cells. Evid Based Complement Alternat Med. 2014;2014:924560. [3]. Wang X, et al. 6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells. PLoS One. 2015 Mar 19;10(3):e0116409. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 450.1±45.0 °C at 760 mmHg Melting Point 234-236 °C(lit.) Molecular Formula C15H10O3 Molecular Weight 238.238 Flash Point 176.3±22.2 °C Exact Mass 238.062988 PSA 50.44000 LogP 3.72 Vapour Pressure 0.0±1.1 mmHg at 25°C Index of Refraction 1.666 InChIKey GPZYYYGYCRFPBU-UHFFFAOYSA-N SMILES O=c1cc(-c2ccccc2)oc2ccc(O)cc12 |
| Use of | Properties Name 6-Hydroxyflavone Synonym More Synonyms 6-Monohydroxyflavone Biological Activity Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Das S, et al. Characterization of non-covalent binding of 6-hydroxyflavone and 5,7-dihydroxyflavone with bovine hemoglobin: Multi-spectroscopic and molecular docking analyses. J Photochem Photobiol B. 2018 Jan;178:40-52. [3]. Wang X, et al. 6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells. PLoS One. 2015 Mar 19;10(3):e0116409. Chemical & Physical Properties Molecular Formula C15H10O3 Exact Mass 238.062988 PSA 50.44000 Index of Refraction 1.666 InChIKey GPZYYYGYCRFPBU-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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